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- Table of Contents
AP2A2 Antibodies
AND AP2A2 ELISA kits, AP2A2 Proteins
Many biological assays use antibodies to detect AP2A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AP2A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AP2A2 antibodies...
Designing a Western blot for AP2A2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AP2A2 Western Blot GuideDesigning an IHC experiment for AP2A2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the AP2A2 IHC GuideAP2A2 Infographic by Boster Bio
All AP2A2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A08527-1
100 μg/vial
Cat # A08527-1
100 μg/vial
Human
$628
Cat # LS000161
20 µg, 100 µg
Cat # LS000161
20 µg, 100 µg
AP2A2 Overview
Facts about AP-2 complex subunit alpha-2.
AP-2 complex subunit alpha-2 (AP2A2)
Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways.
Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome.
Gene Information
| Human | |
|---|---|
| Gene Name: | AP2A2 |
| Uniprot: | O94973 |
| Entrez: | 161 |
Family
| Belongs to: |
|---|
| adaptor complexes large subunit family |
Alternative Names
100 kDa coated vesicle protein C; Adapter-related protein complex 2 alpha-2 subunit; adaptin, alpha B; Adaptor protein complex AP-2 subunit alpha-2; adaptor-related protein complex 2, alpha 2 subunit; alpha2-adaptin; Alpha-adaptin C; alpha-adaptin C; Huntingtin interacting protein J; AP-2 complex subunit alpha-2; Clathrin assembly protein complex 2 alpha-C large chain; clathrin-associated/assembly/adaptor protein, large, alpha 2; DKFZP564D1864; HIP9ADTAB; Huntingtin yeast partner J; Huntingtin-interacting protein 9; Huntingtin-interacting protein J; HYPJCLAPA2; KIAA0899HIP-9; Plasma membrane a
Molecular Weight
Mass (kDA):
103.96 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p15.5 |
| Sequence: | 11; NC_000011.10 (925809..1012245) |
Subcellular Localizations
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV.
Diseases
- Wolff-parkinson-white Syndrome
- Leukemia
- Accessory Atrioventricular Bundle (disorder)
Interacting Proteins
- Dab2
- Kcnj11
Pathways
- Cell Division
- Asymmetric Cell Division
- Cellular Process
- Cytokinesis
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AP2A2
bosterbio.com/bosterbio-gene-info-cards/AP2A2
References
PMID: 9700202 by Faber P.W., et al. Huntingtin interacts with a family of WW domain proteins.
PMID: 11532990 by Waelter S., et al. The huntingtin interacting protein HIP1 is a clathrin and alpha- adaptin-binding protein involved in receptor-mediated endocytosis.