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- Table of Contents
Amyloid-like protein 2 Antibodies
AND APLP2 ELISA kits, Amyloid-like protein 2 Proteins
Many biological assays use antibodies to detect Amyloid-like protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Amyloid-like protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Amyloid-like protein 2 antibodies...
Designing a Western blot for Amyloid-like protein 2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the APLP2 Western Blot GuideDesigning an IHC experiment for Amyloid-like protein 2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the APLP2 IHC GuideAPLP2 Infographic by Boster Bio
All APLP2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01232-1
100 µg/vial
Cat # A01232-1
100 µg/vial
Human, Mouse, Rat
WB
$370
Cat # PA1654-1
100 μg/vial
Cat # PA1654-1
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1035
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1035
1 kit, containing one 96-well plate and all necessary reagents
APLP2 Overview
Facts about Amyloid-like protein 2.
Amyloid-like protein 2 (APLP2)
May play a role in the regulation of hemostasis. The soluble form could have inhibitory properties towards coagulation factors.
May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box).
Gene Information
| Human | |
|---|---|
| Gene Name: | APLP2 |
| Uniprot: | Q06481 |
| Entrez: | 334 |
Family
| Belongs to: |
|---|
| APP family |
Alternative Names
amyloid beta (A4) precursor-like protein 2; amyloid precursor protein homolog HSD-2; Amyloid protein homolog; amyloid-like protein 2; APLP2; APLP-2; APPH; APPHCDEI box-binding protein; APPL2; CDEBP; WALPLP2; YWK-II
Molecular Weight
Mass (kDA):
86.956 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q24.3 |
| Sequence: | 11; NC_000011.10 (130069894..130144811) |
Tissue Specificity
Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Nucleus.
Diseases
- Alzheimer's Disease
- Neuroblastoma
- Senile Plaques
- Tissue Adhesions
- Nervousness
- Plaque, Amyloid
- Neoplasms
- Alzheimer Disease, Familial
- Neurotoxicity Syndromes
- Malignant Neoplasms
- Infertility
- Nerve Degeneration
- Malnutrition
Interacting Proteins
- APLP1
- DEDD
- ETS1
- JUN
- MED12
Pathways
- Pathogenesis
- Secretion
- Cell Death
- Proteolysis
- Cell Adhesion
- Cell Migration
- Transport
- Endocytosis
- Localization
- Synaptic Transmission
- Rna Interference
- Brain Development
- Aging
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Gamma-cleavage
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/APLP2
bosterbio.com/bosterbio-gene-info-cards/APLP2
References
PMID: 8485127 by Sprecher C.A., et al. Molecular cloning of the cDNA for a human amyloid precursor protein homolog: evidence for a multigene family.
PMID: 8220435 by Wasco W., et al. Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor.