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Myb-binding protein 1A Antibodies
AND MYBBP1A ELISA kits, Myb-binding protein 1A Proteins
Many biological assays use antibodies to detect Myb-binding protein 1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Myb-binding protein 1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Myb-binding protein 1A antibodies...
Designing a Western blot for Myb-binding protein 1A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the MYBBP1A Western Blot GuideMYBBP1A Infographic by Boster Bio
All MYBBP1A Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A04187-3
100 μg/vial
Cat # A04187-3
100 μg/vial
MYBBP1A Overview
Facts about Myb-binding protein 1A.
Myb-binding protein 1A (MYBBP1A)
May activate or repress transcription through connections with sequence specific DNA-binding proteins (By similarity). Repression could be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity).
Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | MYBBP1A |
| Uniprot: | Q9BQG0 |
| Entrez: | 10514 |
Family
| Belongs to: |
|---|
| MYBBP1A family |
Alternative Names
MYB binding protein (P160) 1a; myb-binding protein 1A; P160FLJ37886; p53-activated protein-2; PAP2
Molecular Weight
Mass (kDA):
148.855 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.2 |
| Sequence: | 17; NC_000017.11 (4538896..4555386, complement) |
Subcellular Localizations
Cytoplasm. Nucleus. Nucleus, nucleolus. Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity). Predominantly nucleolar.
Diseases
- Neoplasms
- Malignant Neoplasms
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Liver Carcinoma
- Cell Transformation, Neoplastic
- Neoplasm Metastasis
- Sarcoma
- Carcinoma
- Myeloid Leukemia
- Neoplasm Recurrence, Local
- Diabetes Mellitus
Pathways
- Localization
- Cell Cycle
- Chromatin Remodeling
- Cell Proliferation
- Mitosis
- Ribosome Biogenesis
- Nuclear Export
- Cytokinesis
- Nuclear Import
- Methylation
- Cellular Localization
- Cell Growth
- Rrna Transcription
PTMs
- Acetylation
- Methylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYBBP1A
bosterbio.com/bosterbio-gene-info-cards/MYBBP1A
References
PMID: 10644447 by Keough R., et al. Molecular cloning and chromosomal mapping of the human homologue of MYB binding protein (P160) 1A (MYBBP1A) to 17p13.3.
PMID: 16603771 by Cavellan E., et al. The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription.