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Myb-binding protein 1A Antibodies
AND MYBBP1A ELISA kits, Myb-binding protein 1A Proteins
Many biological assays use antibodies to detect Myb-binding protein 1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Myb-binding protein 1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Myb-binding protein 1A antibodies...
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MYBBP1A Infographic by Boster Bio
All MYBBP1A Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M04187
100 μl
Cat # M04187
100 μl
Human, Mouse, Rat
IF, IHC, ICC, WB
$405
Cat # A04187
100ul
Cat # A04187
100ul
Human
Flow Cytometry, IF, IHC, ICC, WB
$405
Cat # A04187-1
100ul
Cat # A04187-1
100ul
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A04187-3
100 μg/vial
Cat # A04187-3
100 μg/vial
MYBBP1A Overview
Facts about Myb-binding protein 1A.
Myb-binding protein 1A (MYBBP1A)
May activate or repress transcription through connections with sequence specific DNA-binding proteins (By similarity). Repression could be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity).
Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | MYBBP1A |
| Uniprot: | Q9BQG0 |
| Entrez: | 10514 |
Family
| Belongs to: |
|---|
| MYBBP1A family |
Alternative Names
MYB binding protein (P160) 1a; myb-binding protein 1A; P160FLJ37886; p53-activated protein-2; PAP2
Molecular Weight
Mass (kDA):
148.855 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.2 |
| Sequence: | 17; NC_000017.11 (4538896..4555386, complement) |
Subcellular Localizations
Cytoplasm. Nucleus. Nucleus, nucleolus. Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity). Predominantly nucleolar.
Diseases
- Neoplasms
- Malignant Neoplasms
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Liver Carcinoma
- Cell Transformation, Neoplastic
- Neoplasm Metastasis
- Sarcoma
- Carcinoma
- Myeloid Leukemia
- Neoplasm Recurrence, Local
- Diabetes Mellitus
Pathways
- Localization
- Cell Cycle
- Chromatin Remodeling
- Cell Proliferation
- Mitosis
- Ribosome Biogenesis
- Nuclear Export
- Cytokinesis
- Nuclear Import
- Methylation
- Cellular Localization
- Cell Growth
- Rrna Transcription
PTMs
- Acetylation
- Methylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYBBP1A
bosterbio.com/bosterbio-gene-info-cards/MYBBP1A
References
PMID: 10644447 by Keough R., et al. Molecular cloning and chromosomal mapping of the human homologue of MYB binding protein (P160) 1A (MYBBP1A) to 17p13.3.
PMID: 16603771 by Cavellan E., et al. The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription.