ARPC2 Antibodies

AND ARPC2 ELISA kits, ARPC2 Proteins

Many biological assays use antibodies to detect ARPC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARPC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARPC2 antibodies...

We validate the specificity of these antibodies to ARPC2 by testing them on tissues known to express ARPC2 positively and negatively. Browse below to find the ARPC2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for ARPC2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the ARPC2 Western Blot Guide

ARPC2 Infographic by Boster Bio

All ARPC2 Products

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Product

Figures

Specificity

Applications

Price

Anti-ARPC2 Rabbit Monoclonal Antibody

Western blot analysis of ARPC2 using anti-ARPC2 antibody (M06165)

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M06165
100 μl/vial

ARPC2 (NM_152862) Human Over-expression Lysate

ARPC2 Human Over-expression Lysates NM_005731

Human

$628
Cat # LS010109
20 µg, 100 µg

Human ARPC2 Recombinant Protein

SDS-PAGE

$250
Cat # PROTO15144
Starting from 4ug

ARPC2 Overview

Facts about Actin-related protein 2/3 complex subunit 2.

ARPC2 3D structure. Source: alphafold

Actin-related protein 2/3 complex subunit 2 (ARPC2)

Actin-binding part of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079).

Seems to contact the mother actin filament (PubMed:9230079). Besides its function in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947).

Gene Information

Human
Gene Name:	ARPC2
Uniprot:	O15144
Entrez:	10109

Family

Belongs to:

ARPC2 family

Alternative Names

actin related protein 2/3 complex, subunit 2 (34 kD); actin related protein 2/3 complex, subunit 2, 34kDa; ARC34actin-related protein 2/3 complex subunit 2; Arp2/3 complex 34 kDa subunit; ARP2/3 protein complex subunit 34; p34-Arc; PNAS-139

Molecular Weight

Mass (kDA):
34.333 kDA

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (218217138..218254348)

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell projection. Cell junction, synapse, synaptosome. Nucleus.

Diseases

Ulcer
Colitis
Tissue Adhesions
Ulcerative Colitis
Wiskott-aldrich Syndrome
Melanoma
Inflammatory Bowel Diseases
Swine Diseases
Intestinal Diseases
Dysplasia
Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Pancreas

Bulla
Infective Disorder
Malignant Paraganglionic Neoplasm
Nevi And Melanomas
Gastrointestinal Infection
Melanocytic Nevus
Dysplastic Nevus

Interacting Proteins

CORO1B
VCL

Pathways

Actin Nucleation
Endocytosis
Localization
Cell Migration
Establishment Of Cell Polarity
Locomotion
Pathogenesis
Mitosis
Cytokinesis
Phagocytosis

Cell Growth
Stomatal Movement
Meiosis
Cell-cell Adhesion

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARPC2

References

PMID: 9230079 by Welch M.D., et al. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.

PMID: 8812419 by Couch F.J., et al. Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13.