ASPH Antibodies

AND ASPH ELISA kits, ASPH Proteins

Many biological assays use antibodies to detect ASPH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ASPH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ASPH antibodies...

We validate the specificity of these antibodies to ASPH by testing them on tissues known to express ASPH positively and negatively. Browse below to find the ASPH antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ASPH Infographic by Boster Bio

All ASPH Products

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Product

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Specificity

Applications

Price

Anti-Aspartate beta hydroxylase/ASPH Antibody Picoband®

1 Citations 7 Q&As

Western blot analysis of ASPH using anti-ASPH antibody (PB9478)

Immunoblotting detection of the ASPH protein

The effect of ASPH inhibition on cell proliferation

Human, Mouse, Rat

Flow Cytometry, IHC, ICC, WB

$370
Cat # PB9478
100 μg/vial

Aspartate beta hydroxylase (ASPH) (NM_032466) Human Recombinant Protein

Coomassie blue staining of purified ASPH protein

$1249
Cat # PROTQ12797
20 µg

Aspartate beta hydroxylase (ASPH) (NM_004318) Human Over-expression Lysate

Aspartate beta hydroxylase (ASPH) Human Over-expression Lysates NM_001164752

Human

$960
Cat # LS000444
20 µg, 100 µg

ASPH Overview

Facts about Aspartyl/asparaginyl beta-hydroxylase.

ASPH 3D structure. Source: alphafold

Aspartyl/asparaginyl beta-hydroxylase (ASPH)

Isoform 1: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins. .

Gene Information

Human
Gene Name:	ASPH
Uniprot:	Q12797
Entrez:	444

Family

Belongs to:

aspartyl/asparaginyl beta-hydroxylase family

Alternative Names

AAH; ASP beta-hydroxylase; aspartate beta-hydroxylaseA beta H-J-J; aspartyl/asparaginyl-beta-hydroxylase; BAH; cardiac junctin; CASQ2BP1; EC 1.14.11.16; HAAHaspartyl/asparaginyl beta-hydroxylase; humbug; JCTN; junctate; junctin; Peptide-aspartate beta-dioxygenase

Molecular Weight

Mass (kDA):
85.863 kDA

Genomic Context


Human

Location:	8q12.3
Sequence:	8; NC_000008.11 (61500556..61714640, complement)

Tissue Specificity

Isoform 1 is detected in all tissues tested. Isoform 8 is mainly expressed in pancreas, heart, brain, kidney and liver. Isoform 8 is expressed in kidney (at protein level).

Subcellular Localizations

[Isoform 1]: Endoplasmic reticulum membrane; Single-pass type II membrane protein.; [Isoform 4]: Sarcoplasmic reticulum membrane; Single-pass type II membrane protein.; [Isoform 8]: Endoplasmic reticulum membrane; Single-pass type II membrane protein.

Diseases

Cardiac Arrhythmia
Hypertrophy
Heart Failure
Neoplasms
Tachycardia, Ventricular
Endometriosis, Site Unspecified
Neoplasm Metastasis
Cardiac Hypertrophy
Malignant Neoplasms
Polymorphic Ventricular Tachycardia
Carcinoma
Heart Diseases
Cholangiocarcinoma

Hemorrhage
Sudden Death
Liver Carcinoma
Malignant Paraganglionic Neoplasm
Cataract
Cell Invasion
Atrial Fibrillation

Interacting Proteins

ASNA1

Pathways

Localization
Cell Migration
Regulation Of Muscle Contraction
Transport
Fertilization
Dna Methylation
Glycosylation
Immune Response
Muscle Contraction
Methylation
Drug Resistance
Muscle Hypertrophy
Translation

Acrosome Reaction
Cell Motility
Cell Differentiation
Pathogenesis
Eye Development
Rna Interference
Secretion

PTMs

Phosphorylation
Hydroxylation

Glycosylation
Methylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ASPH

References

PMID: 7821814 by Korioth F., et al. Cloning and characterization of the human gene encoding aspartyl beta-hydroxylase.

PMID: 8823296 by Lavaissiere L., et al. Overexpression of human aspartyl(asparaginyl)beta-hydroxylase in hepatocellular carcinoma and cholangiocarcinoma.