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- Table of Contents
ATG16L1 Antibodies
AND ATG16L1 ELISA kits, ATG16L1 Proteins
Many biological assays use antibodies to detect ATG16L1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ATG16L1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ATG16L1 antibodies...
Designing a Western blot for ATG16L1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ATG16L1 Western Blot GuideDesigning an IHC experiment for ATG16L1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ATG16L1 IHC GuideATG16L1 Infographic by Boster Bio
All ATG16L1 Products
Product
Figures
Specificity
Applications
Price
Anti-Atg16L1/Atg16 Rabbit Monoclonal Antibody
2 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # M00526
100 μl
Cat # M00526
100 μl
ATG16L1 Overview
Facts about Autophagy-related protein 16-1.
Autophagy-related protein 16-1 (ATG16L1)
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Gene Information
| Human | |
|---|---|
| Gene Name: | ATG16L1 |
| Uniprot: | Q676U5 |
| Entrez: | 55054 |
Family
| Belongs to: |
|---|
| WD repeat ATG16 family |
Alternative Names
APG16 autophagy 16-like (S. cerevisiae); APG16L beta; APG16LFLJ10828; APG16-like 1; ATG16 autophagy related 16-like (S. cerevisiae); ATG16 autophagy related 16-like 1 (S. cerevisiae); ATG16A; ATG16L; autophagy-related protein 16-1; FLJ00045; FLJ10035; FLJ22677; IBD10; WD repeat domain 30; WDR30
Molecular Weight
Mass (kDA):
68.265 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q37.1 |
| Sequence: | 2; NC_000002.12 (233251571..233295674) |
Subcellular Localizations
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Recruited to omegasomes membranes by WIPI2. Omegasomes are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Localized to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. Localizes also to discrete punctae along the ciliary axoneme.
Diseases
- Crohn Disease
- Inflammatory Bowel Diseases
- Intestinal Diseases
- Ulcerative Colitis
- Colitis
- Ulcer
- Inflammation
- Inflammatory Disorder
- Malignant Neoplasms
- Bacterial Infections
- Chronic Inflammation
- Innate Immune Response
- Dysequilibrium Syndrome
Interacting Proteins
- ATG5
- GABARAPL2
- MAP1LC3B
- MAP1LC3C
- RB1CC1
- TMEM59
Pathways
- Autophagy
- Pathogenesis
- Immune Response
- Secretion
- Macroautophagy
- Innate Immune Response
- Inflammatory Response
- Cytokine Production
- Localization
- Adaptive Immune Response
- Exocytosis
- Catabolic Process
- Conjugation
PTMs
Research Areas
- Autophagy
- Cancer
- Cell Biology
- Macroautophagy
- Neurodegeneration
- Neuroscience
- Tumor Suppressors
- Ubiquitin Proteasome Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ATG16L1
bosterbio.com/bosterbio-gene-info-cards/ATG16L1
References
PMID: 15620219 by Zheng H., et al. Cloning and analysis of human Apg16L.
PMID: 17200669 by Hampe J., et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1.