Arhgap18 Antibodies

AND Arhgap18 ELISA kits, Arhgap18 Proteins

Many biological assays use antibodies to detect Arhgap18, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Arhgap18 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Arhgap18 antibodies...

We validate the specificity of these antibodies to Arhgap18 by testing them on tissues known to express Arhgap18 positively and negatively. Browse below to find the Arhgap18 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Arhgap18? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the ARHGAP18 IHC Guide

Arhgap18 Infographic by Boster Bio

All Arhgap18 Products

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Applications

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Anti-ARHGAP18 Antibody

Western blot analysis of ARHGAP18 in 3T3 cell lysate with ARHGAP18 antibody at (A) 1 and (B) 2 μg/mL

Immunocytochemistry of ARHGAP18 in 3T3 cells with ARHGAP18 antibody at 2

Immunofluorescence of ARHGAP18 in 3T3 cells with ARHGAP18 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, ICC, WB

$481
Cat # A08418-1
0.1 mg

Anti-ARHGAP18 Antibody

Western Blot analysis of various cells using ARHGAP18 Polyclonal Antibody

Western Blot analysis of Jurkat cells using ARHGAP18 Polyclonal Antibody

Human, Mouse

ELISA, IF, IHC, WB

$399
Cat # A08418
100μl

ARHGAP18 (NM_033515) Human Over-expression Lysate

Human

$628
Cat # LS093663
20 µg, 100 µg

Arhgap18 Overview

Facts about Rho GTPase-activating protein 18.

Rho GTPase-activating protein 18 (Arhgap18)

Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases into an inactive GDP-bound state.

Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which then reduces nuclear localization of YAP1.

Gene Information

Mouse
Gene Name:	Arhgap18
Uniprot:	Q8K0Q5
Entrez:	73910

Family

Belongs to:

No superfamily

Alternative Names

bA307O14.2; MacGAP; MGC126757; Rho GTPase activating protein 18; rho-type GTPase-activating protein 18

Molecular Weight

Mass (kDA):
74.93 kDA

Genomic Context


Mouse

Location:	10\|10 A4
Sequence:	10;

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Schizophrenia
Carcinogenesis
Neoplasms
Malignant Neoplasm Of Kidney
Brain Neoplasms
Malignant Neoplasm Of Lung
Animal Mammary Neoplasms
Chondrosarcoma
Leukemia

Mammary Neoplasms
Malignant Neoplasm Of Pancreas
Lymphoid Leukemia
Chronic Lymphocytic Leukemia
Neuroendocrine Tumors

Pathways

Cell Proliferation
Brain Development
Methylation
Cell Migration
Translation
Gene Silencing
Dna Methylation

Mrna Processing
Cell Growth

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Arhgap18

References

PMID: 21865595 by Maeda M., et al. ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility.