Arylsulfatase B Antibodies

AND ARSB ELISA kits, Arylsulfatase B Proteins

Many biological assays use antibodies to detect Arylsulfatase B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Arylsulfatase B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Arylsulfatase B antibodies...

We validate the specificity of these antibodies to Arylsulfatase B by testing them on tissues known to express ARSB positively and negatively. Browse below to find the ARSB antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Arylsulfatase B? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the ARSB IHC Guide

ARSB Infographic by Boster Bio

All ARSB Products

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Product

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Specificity

Applications

Price

Human ARSB/Arylsulfatase B ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2078
96 wells/kit, with removable strips.

Anti-Arsb Antibody Picoband®

Western blot analysis of Arsb using anti-Arsb antibody (A01609-3)

Mouse, Rat

$370
Cat # A01609-3
100 μg/vial

Anti-Arylsulfatase B ARSB Antibody

Western blot analysis of ARSB in mouse lung tissue lysate with ARSB antibody at (A) 1 and (B) 2 μg/ml

Immunohistochemistry of ARSB in human lung tissue with ARSB antibody at 2

Immunofluorescence of ARSB in human lung tissue with ARSB antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A01609
0.1 mg

ARSB (NM_000046) Human Over-expression Lysate

ARSB Human Over-expression Lysates NM_000046

Human

$960
Cat # LS000411
20 µg, 100 µg

ARSB (NM_198709) Human Recombinant Protein

Coomassie blue staining of purified ARSB protein

$1249
Cat # PROTP15848
20 µg

ARSB Overview

Facts about Arylsulfatase B.

ARSB 3D structure. Source: alphafold

Arylsulfatase B (ARSB)

Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (PubMed:19306108). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (PubMed:19306108).

In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). .

Gene Information

Human
Gene Name:	ARSB
Uniprot:	P15848
Entrez:	411

Family

Belongs to:

sulfatase family

Alternative Names

ARSB; Arylsulfatase B; ASB; EC 3.1.6.12; G4S; MPS6; N-acetylgalactosamine-4-sulfatase

Molecular Weight

Mass (kDA):
59.687 kDA

Genomic Context


Human

Location:	5q14.1
Sequence:	5; NC_000005.10 (78777209..78986087, complement)

Subcellular Localizations

Lysosome. Cell surface.

Diseases

Mucopolysaccharidoses
Mucopolysaccharidosis Vi
Overgrowth Bacterial
Hereditary Diseases
Mucopolysaccharidosis Iv
Storage Disease
Lysosomal Storage Diseases
Deficiency Of Arylsulfatase
Malignant Paraganglionic Neoplasm
Menkes Kinky Hair Syndrome
Steroid Sulfatase Deficiency Disease
Arsenic Poisoning
Hepatolenticular Degeneration

Nervousness
Pfaundler-hurler Syndrome
Malignant Neoplasms
Dwarfism
Compression Of Spinal Cord
Atrophy
Hypokinesia

Pathways

Transport
Localization
Excretion
Secretion
Arsenite Transport
Sulfation
Transposition
Conjugation
Cell Growth
Cell Migration
Quorum Sensing
Photosynthesis
Proteolysis

Immune Response
Hypersensitivity
Virulence
Flight
Nitrogen Fixation
Protein Refolding
Epithelial Cell Migration

PTMs

Reduction

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARSB

References

PMID: 2303452 by Peters C., et al. Phylogenetic conservation of arylsulfatases. cDNA cloning and expression of human arylsulfatase B.

PMID: 1968043 by Schuchman E.H., et al. Human arylsulfatase B: MOPAC cloning, nucleotide sequence of a full- length cDNA, and regions of amino acid identity with arylsulfatases A and C.