BAG4 Antibodies

AND BAG4 ELISA kits, BAG4 Proteins

Many biological assays use antibodies to detect BAG4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BAG4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BAG4 antibodies...

We validate the specificity of these antibodies to BAG4 by testing them on tissues known to express BAG4 positively and negatively. Browse below to find the BAG4 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for BAG4? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the BAG4 IHC Guide

BAG4 Infographic by Boster Bio

All BAG4 Products

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Specificity

Applications

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Anti-SODD BAG4 Antibody

Western blot analysis of SODD in HeLa (1,3) and THP-1 (2,4) whole cell lysates in the absence (1,2) or presence (3,4) of blocking peptide (Catalog no

Immunocytochemistry of SODD in HeLa cells with SODD antibody at 5 μg/mL

Immunofluorescence of SODD in Hela cells with SODD antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, ICC, WB

$481
Cat # A06722
0.1 mg

Anti-Bag-4 Antibody

Western Blot analysis of various cells using Bag-4 Polyclonal Antibody

Western Blot analysis of K562 cells using Bag-4 Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded human tonsil

Human, Mouse, Rat

ELISA, IF, IHC, WB

$399
Cat # A06722-1
100μl

Silencer of Death Domain (BAG4) (NM_004874) Human Over-expression Lysate

Human

$628
Cat # LS009530
20 µg, 100 µg

Anti-Bag-4 (V442) Antibody

Western blot (WB) analysis of Bag-4 (V442) pAb at 1:500 dilution
Lane1:A375 whole cell lysate(40ug)
Lane2:HEK293T whole cell lysate(40ug)
Lane3:Hela whole cell lysate(40ug)
Lane4:3T3-L1 whole cell lysate(40ug)
Lane5:PC12 whole cell lysate(40ug)

Human, Mouse, Rat

IHC, WB

$405
Cat # A06722-2
100ul

Silencer of Death Domain (BAG4) (NM_004874) Human Recombinant Protein

Coomassie blue staining of purified BAG4 protein

$1062
Cat # PROTO95429
20 µg

BAG4 Overview

Facts about BAG family molecular chaperone regulator 4.

BAG4 3D structure. Source: alphafold

BAG family molecular chaperone regulator 4 (BAG4)

Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling.

Negative regulator of PRKN translocation to damaged mitochondria. .

Gene Information

Human
Gene Name:	BAG4
Uniprot:	O95429
Entrez:	9530

Family

Belongs to:

No superfamily

Alternative Names

BAG4; BAG-4; BAG-family molecular chaperone regulator-4; Bcl-2-associated athanogene 4; BCL2-associated athanogene 4; Silencer of death domains; SODD; SODDBAG family molecular chaperone regulator 4

Molecular Weight

Mass (kDA):
49.594 kDA

Genomic Context


Human

Location:	8p11.23
Sequence:	8; NC_000008.11 (38176855..38213301)

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Colonic Neoplasms
Mammary Neoplasms
Malignant Neoplasm Of Breast
Cell Transformation, Neoplastic
Leukemia
Neoplasm Metastasis
Epithelial Ovarian Cancer
Ovarian Neoplasm
Inflammation

Pancreatic Neoplasm
Malignant Neoplasm Of Ovary
Tissue Adhesions
Stomach Neoplasms
Malignant Tumor Of Colon
Malignant Tumor Of Cervix
Ulcer

Interacting Proteins

DCP1A
DCP1B
DNAJC7
HSPA1L
HSPA2

HSPA8
TBC1D7
TSG101

Pathways

Cell Death
Localization
Transport
Intracellular Transport
Cell Migration
Apoptotic Signaling Pathway
Fertilization
Regulation Of Gene Expression
Metaphase
Drug Resistance

Translation
Cell Cycle
Pathogenesis
Apoptotic Process

PTMs

Phosphorylation

Research Areas

Apoptosis
Cancer
Mitochondrial-Mediated Pathway
Tumor Suppressors

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BAG4

References

PMID: 9873016 by Takayama S., et al. An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators.

PMID: 9915703 by Jiang Y., et al. Prevention of constitutive TNF receptor 1 signaling by silencer of death domains.