BMPR1A Antibodies

AND BMPR1A ELISA kits, BMPR1A Proteins

Many biological assays use antibodies to detect BMPR1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with BMPR1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop BMPR1A antibodies...

We validate the specificity of these antibodies to BMPR1A by testing them on tissues known to express BMPR1A positively and negatively. Browse below to find the BMPR1A antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for BMPR1A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the BMPR1A Western Blot Guide

Designing an IHC experiment for BMPR1A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the BMPR1A IHC Guide

BMPR1A Infographic by Boster Bio

All BMPR1A Products

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Product

Figures

Specificity

Applications

Price

Anti-BMPR1A Antibody Picoband®

Western blot analysis of BMPR1A using anti-BMPR1A antibody (A01581-1)

IHC analysis of BMPR1A using anti-BMPR1A antibody (A01581-1)

Flow Cytometry analysis of MCF-7 cells using anti-BMPR1A antibody (A01581-1)

Human, Rat

Flow Cytometry, IHC, WB

$370
Cat # A01581-1
100 μg/vial

BMPR1A (NM_004329) Human Over-expression Lysate

Human

$628
Cat # LS000657
20 µg, 100 µg

BMPR1A (NM_004329) Human Recombinant Protein

Coomassie blue staining of purified BMPR1A protein

$1062
Cat # PROTP36894
20 µg

Anti-BMPR1A Antibody (C-term)

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining

Western blot analysis of anti-BMPR1A Pab (Cat

Western blot analysis of lysates from 293, mouse NIH/3T3 cell line (from left to right), using BMPR1A Antibody (C180)

Human, Mouse

IHC-P, WB

$299
Cat # A01581
80 µl

BMPR1A Overview

Facts about Bone morphogenetic protein receptor type-1A.

BMPR1A 3D structure. Source: alphafold

Bone morphogenetic protein receptor type-1A (BMPR1A)

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.

Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction.

Gene Information

Human
Gene Name:	BMPR1A
Uniprot:	P36894
Entrez:	657

Family

Belongs to:

protein kinase superfamily

Alternative Names

ACVRLK310q23del; ALK-3; ALK3EC 2.7.11.30; BMP type-1A receptor; BMPR1A; BMPR-1A; BMPRIA; BMPR-IA; bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor, type IA; CD292 antigen; CD292; EC 2.7.11; Serine/threonine-protein kinase receptor R5; SKR5; type II-like kinase 3

Molecular Weight

Mass (kDA):
60.198 kDA

Genomic Context


Human

Location:	10q23.2
Sequence:	10; NC_000010.11 (86755786..86927969)

Tissue Specificity

Highly expressed in skeletal muscle.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cell surface.

Diseases

Polyposis
Malignant Neoplasms
Juvenile Polyposis Syndrome
Neoplasms
Polyps
Adenomatous Polyposis Coli
Colorectal Cancer
Intestinal Polyposis
Nervousness
Colonic Neoplasms
Colorectal Neoplasms
Hamartoma Syndrome, Multiple
Neoplasm Metastasis

Peutz-jeghers Syndrome
Carcinoma
Hyperplasia
Neoplastic Syndromes, Hereditary
Malignant Tumor Of Colon
Malignant Neoplasm Of Breast
Germline Mutation Abnormality

Interacting Proteins

BMP2
BMP4
GDF5

Pathways

Cell Proliferation
Cell Differentiation
Osteoblast Differentiation
Pathogenesis
Localization
Bmp Signaling Pathway
Regeneration
Gastrulation
Cell Growth
Angiogenesis
Ossification
Cell Cycle
Cell Death

Mismatch Repair
Secretion
Neurogenesis
Bone Resorption
Lung Development
Bone Morphogenesis
Endochondral Ossification

PTMs

Phosphorylation
Sumoylation

Cleavage
Deglycosylation

Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/BMPR1A

References

PMID: 8397373 by ten Dijke P., et al. Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity.

PMID: 22799562 by Mahlawat P., et al. Structure of the Alk1 extracellular domain and characterization of its bone morphogenetic protein (BMP) binding properties.