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- Table of Contents
Designing an IHC experiment for BCAP31? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the BCAP31 IHC GuideFacts about B-cell receptor-associated protein 31.
Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins.
| Human | |
|---|---|
| Gene Name: | BCAP31 |
| Uniprot: | P51572 |
| Entrez: | 10134 |

| Belongs to: |
|---|
| BCAP29/BCAP31 family |

6C6-Ag; BAP31; Bap31,6C6-AG; BAP31DXS1357ECDM; BCAP31; B-cell receptor-associated protein 31; BCR-associated protein 31; BCR-associated protein Bap31,6C6-AG tumor-associated antigen; p28 Bap31,6C6-Ag; p28; Protein CDM
Mass (kDA):
27.992 kDA

| Human | |
|---|---|
| Location: | Xq28 |
| Sequence: | X; NC_000023.11 (153700492..153724746, complement) |
Ubiquitous. Highly expressed in neurons and discrete endocrine cells.
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. May shuttle between the ER and the intermediate compartment/cis-Golgi complex.






PMID: 7806238 by Mosser J., et al. A new human gene (DXS1357E) with ubiquitous expression, located in Xq28 adjacent to the adrenoleukodystrophy gene.
PMID: 8706661 by Li E., et al. Molecular cloning and characterization of a transmembrane surface antigen in human cells.