Many biological assays use antibodies to detect Complement C5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Complement C5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Complement C5 antibodies...
We validate the specificity of these antibodies to Complement C5 by testing them on tissues known to express C5 positively and negatively. Browse below to find the C5 antibody that suites your experiment. We have 52 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Designing a Western blot for Complement C5?
The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, in the membrane attack complex. C5b has a transient binding site for C6.
The C5b-C6 complicated is the foundation upon which the lytic complex is constructed. .
For details, visit: bosterbio.com/bosterbio-gene-info-cards/C5
References
PMID: 1984448 by Haviland D.L., et al. Complete cDNA sequence of human complement pro-C5. Evidence of truncated transcripts derived from a single copy gene.
PMID: 3365401 by Wetsel R.A., et al. Molecular analysis of human complement component C5: localization of the structural gene to chromosome 9.
5 Publications of Boster Complement C5 Antibodies & ELISA Kits
PubMed ID: 10.1016/j.jtcvs.2018.09.017, Effect of preoperative inhaled budesonide on pulmonary injury after cardiopulmon...
PubMed ID: 10.1016/j.envpol.2016.07.073, Cadmium-induced immune abnormality is a key pathogenic event in human and rat mo...