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- Table of Contents
Complement component C9 Antibodies
AND C9 ELISA kits, Complement component C9 Proteins
Many biological assays use antibodies to detect Complement component C9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Complement component C9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Complement component C9 antibodies...
Designing a Western blot for Complement component C9? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the C9 Western Blot GuideC9 Infographic by Boster Bio
All C9 Products
Product
Figures
Specificity
Applications
Price
Anti-TRPM2 Antibody Picoband®
2 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01013-1
100 μg/vial
Cat # A01013-1
100 μg/vial
Anti-Complement C9 Antibody Picoband®
2 Citations
Human, Mouse
ELISA, WB
$370
Cat # A01010-2
100 μg/vial
Cat # A01010-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC-P, WB
$370
Cat # A00419-1
100 μg/vial
Cat # A00419-1
100 μg/vial
C9 Overview
Facts about Complement component C9.
Complement component C9 (C9)
Constituent of the membrane attack complex (MAC) which plays an integral role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells (PubMed:9634479, PubMed:9212048, PubMed:26841934). C9 is the pore- forming subunit of the MAC (PubMed:4055801, PubMed:26841934).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | C9 |
| Uniprot: | P02748 |
| Entrez: | 735 |
Family
| Belongs to: |
|---|
| complement C6/C7/C8/C9 family |
Alternative Names
complement component 9; Complement Component C9
Molecular Weight
Mass (kDA):
63.173 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5p13.1 |
| Sequence: | 5; NC_000005.10 (39284140..39364495, complement) |
Tissue Specificity
Plasma (at protein level).
Subcellular Localizations
Secreted. Target cell membrane; Multi-pass membrane protein. Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore.
Diseases
- Hemolysis (disorder)
- Inflammation
- Neoplasms
- Malignant Neoplasms
- Glomerulonephritis
- Infective Disorder
- Lupus Erythematosus, Systemic
- Kidney Diseases
- Arthritis
- Proteinuria Of Undiagnosed Cause
- Edema
- Rheumatoid Arthritis
- Melanoma
Pathways
- Complement Activation
- Pathogenesis
- Localization
- Cell Death
- Secretion
- Cytolysis
- Transport
- Proteolysis
- Immune Response
- Glycosylation
- Coagulation
- Virulence
- Inflammatory Response
PTMs
- Cleavage
- Oxidation
- Phosphorylation
- Glycosylation
- Reduction
- Acetylation
- Hydroxylation
- Methylation
- Carboxylation
- Acylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C9
bosterbio.com/bosterbio-gene-info-cards/C9
References
PMID: 4018030 by Stanley K.K., et al. The sequence and topology of human complement component C9.
PMID: 6095282 by Discipio R.G., et al. Nucleotide sequence of cDNA and derived amino acid sequence of human complement component C9.