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- Table of Contents
Caspase-10 Antibodies
AND CASP10 ELISA kits, Caspase-10 Proteins
Many biological assays use antibodies to detect Caspase-10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caspase-10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caspase-10 antibodies...
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CASP10 Infographic by Boster Bio
All CASP10 Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, WB
$370
Cat # PA1513
100 μg/vial
Cat # PA1513
100 μg/vial
Human
Flow Cytometry, IP, IHC, WB
$370
Cat # M02190-1
100 μl
Cat # M02190-1
100 μl
Human, Mouse
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02190
100 μl
Cat # M02190
100 μl
Human
ELISA
$480
Cat # EKC1084
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1084
1 kit, containing one 96-well plate and all necessary reagents
Anti-Caspase-10/CASP10 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, WB
$370
Cat # A02190-2
100 μg/vial
Cat # A02190-2
100 μg/vial
CASP10 Overview
Facts about Caspase-10.
Caspase-10 (CASP10)
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner.
May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase- 3, -4, -6, -7, -8, and -9.
Gene Information
| Human | |
|---|---|
| Gene Name: | CASP10 |
| Uniprot: | Q92851 |
| Entrez: | 843 |
Family
| Belongs to: |
|---|
| peptidase C14A family |
Alternative Names
Apoptotic protease Mch-4; CASP10; CASP-10; caspase 10, apoptosis-related cysteine peptidase; caspase 10, apoptosis-related cysteine protease; Caspase10; Caspase-10; EC 3.4.22.63; FADD-like ICE2; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4; interleukin-1B-converting enzyme 2; Mch4; MCH4ALPS2
Molecular Weight
Mass (kDA):
58.951 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q33.1 |
| Sequence: | 2; NC_000002.12 (201182885..201229406) |
Tissue Specificity
Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon.
Diseases
- Malignant Neoplasms
- Neoplasms
- Autoimmune Lymphoproliferative Syndrome
- Autoimmune Reaction
- Mammary Neoplasms
- Carcinoma
- Autoimmune Diseases
- Lymphoproliferative Disorders
- Leukemia
- Malignant Neoplasm Of Breast
- Malignant Neoplasm Of Lung
- Neuroblastoma
- Lung Neoplasms
Interacting Proteins
- CASP8
- CFLAR
- RIOK3
- RIPK1
- XIAP
Pathways
- Cell Death
- Pathogenesis
- Programmed Cell Death
- Methylation
- Cell Proliferation
- Induction Of Apoptosis
- Cell Cycle
- Localization
- Cell Growth
- Mitochondrial Depolarization
- Transport
- Gene Silencing
- Proteolysis
PTMs
- Cleavage
- Phosphorylation
- Methylation
Research Areas
- Apoptosis
- Breast Cancer
- Cancer
- Caspases
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CASP10
bosterbio.com/bosterbio-gene-info-cards/CASP10
References
PMID: 8755496 by Fernandes-Alnemri T., et al. In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.
PMID: 9045686 by Vincenz C., et al. Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling.
2 Publications of Boster Caspase-10 Antibodies & ELISA Kits
- PubMed ID: 10.1097/CEJ.0b013e3283431c08, Profile of protein expression of the colon cancer cell line SW480 with survivin/...
- PubMed ID: 23810797, Chen K, Shu G, Peng X, Fang J, Cui H, Chen J, Wang F, Chen Z, Zuo Z, Deng J, Gen...
*More publications can be found for each product on its corresponding product page