This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Caspase-10 Antibodies
AND CASP10 ELISA kits, Caspase-10 Proteins
Many biological assays use antibodies to detect Caspase-10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caspase-10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caspase-10 antibodies...
Designing a Western blot for Caspase-10? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CASP10 Western Blot GuideCASP10 Infographic by Boster Bio
All CASP10 Products
Product
Figures
Specificity
Applications
Price
Anti-Caspase-10/CASP10 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, WB
$370
Cat # A02190-2
100 μg/vial
Cat # A02190-2
100 μg/vial
Human, Mouse
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02190
100 μl
Cat # M02190
100 μl
Human
Flow Cytometry, IP, IHC, WB
$370
Cat # M02190-1
100 μl
Cat # M02190-1
100 μl
Human
ELISA
$480
Cat # EKC1084
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1084
1 kit, containing one 96-well plate and all necessary reagents
Enzyme Activity, SDS-PAGE
$243
Cat # PROTQ13427
Starting from 20ug
Cat # PROTQ13427
Starting from 20ug
CASP10 Overview
Facts about Caspase-10.
Caspase-10 (CASP10)
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner.
May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase- 3, -4, -6, -7, -8, and -9.
Gene Information
| Human | |
|---|---|
| Gene Name: | CASP10 |
| Uniprot: | Q92851 |
| Entrez: | 843 |
Family
| Belongs to: |
|---|
| peptidase C14A family |
Alternative Names
Apoptotic protease Mch-4; CASP10; CASP-10; caspase 10, apoptosis-related cysteine peptidase; caspase 10, apoptosis-related cysteine protease; Caspase10; Caspase-10; EC 3.4.22.63; FADD-like ICE2; FAS-associated death domain protein interleukin-1B-converting enzyme 2; FLICE2; ICE-like apoptotic protease 4; interleukin-1B-converting enzyme 2; Mch4; MCH4ALPS2
Molecular Weight
Mass (kDA):
58.951 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q33.1 |
| Sequence: | 2; NC_000002.12 (201182885..201229406) |
Tissue Specificity
Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon.
Diseases
- Malignant Neoplasms
- Neoplasms
- Autoimmune Lymphoproliferative Syndrome
- Autoimmune Reaction
- Mammary Neoplasms
- Carcinoma
- Autoimmune Diseases
- Lymphoproliferative Disorders
- Leukemia
- Malignant Neoplasm Of Breast
- Malignant Neoplasm Of Lung
- Neuroblastoma
- Lung Neoplasms
Interacting Proteins
- CASP8
- CFLAR
- RIOK3
- RIPK1
- XIAP
Pathways
- Cell Death
- Pathogenesis
- Programmed Cell Death
- Methylation
- Cell Proliferation
- Induction Of Apoptosis
- Cell Cycle
- Localization
- Cell Growth
- Mitochondrial Depolarization
- Transport
- Gene Silencing
- Proteolysis
PTMs
- Cleavage
- Phosphorylation
- Methylation
Research Areas
- Apoptosis
- Breast Cancer
- Cancer
- Caspases
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CASP10
bosterbio.com/bosterbio-gene-info-cards/CASP10
References
PMID: 8755496 by Fernandes-Alnemri T., et al. In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.
PMID: 9045686 by Vincenz C., et al. Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling.
2 Publications of Boster Caspase-10 Antibodies & ELISA Kits
- PubMed ID: 10.1097/CEJ.0b013e3283431c08, Profile of protein expression of the colon cancer cell line SW480 with survivin/...
- PubMed ID: 23810797, Chen K, Shu G, Peng X, Fang J, Cui H, Chen J, Wang F, Chen Z, Zuo Z, Deng J, Gen...
*More publications can be found for each product on its corresponding product page