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- Table of Contents
Caspase-7 Antibodies
AND CASP7 ELISA kits, Caspase-7 Proteins
Many biological assays use antibodies to detect Caspase-7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caspase-7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caspase-7 antibodies...
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CASP7 Infographic by Boster Bio
All CASP7 Products
Product
Figures
Specificity
Applications
Price
Anti-Caspase-7/CASP7 Antibody Picoband®
1 Citations 1 Q&As
Human, Rat
IHC, WB
$370
Cat # PB9369
100 μg/vial
Cat # PB9369
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1442
100 μg/vial
Cat # PA1442
100 μg/vial
Anti-Cleaved-Caspase-7 (S199) CASP7 Antibody
1 Citations
Human, Mouse
ELISA, IF, IHC, WB
$380
Cat # A01044S199
100ul
Cat # A01044S199
100ul
Anti-Caspase-7/CASP7 Antibody Picoband®
1 Citations
Human, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01044-2
100 μg/vial
Cat # A01044-2
100 μg/vial
CASP7 Overview
Facts about Caspase-7.
Caspase-7 (CASP7)
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs).
Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) in a'216-Asp-.
Gene Information
| Human | |
|---|---|
| Gene Name: | CASP7 |
| Uniprot: | P55210 |
| Entrez: | 840 |
Family
| Belongs to: |
|---|
| peptidase C14A family |
Alternative Names
apoptosis-related cysteine protease; Apoptotic protease Mch-3; CASP7; CASP-7; caspase 7, apoptosis-related cysteine peptidase; Caspase7; Caspase-7; EC 3.4.22; EC 3.4.22.60; ICE-like apoptotic protease 3; Lice2 alpha/beta/gamma; Mch3
Molecular Weight
Mass (kDA):
34.277 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q25.3 |
| Sequence: | 10; NC_000010.11 (113679162..113730909) |
Tissue Specificity
Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Leukemia
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Malignant Neoplasm Of Lung
- Lung Neoplasms
- Prostatic Neoplasms
- Adenocarcinoma
- Inflammation
- Malignant Neoplasm Of Prostate
Interacting Proteins
- BIRC2
- NIF3L1
- PAK2
- SAT1
- SMPD1
- XIAP
Pathways
- Cell Death
- Induction Of Apoptosis
- Cell Cycle
- Proteolysis
- Cell Proliferation
- Cell Growth
- Programmed Cell Death
- Apoptotic Process
- Localization
- Pathogenesis
- Cell Cycle Arrest
- Secretion
- Sensitization
PTMs
- Cleavage
- Phosphorylation
- Ubiquitination
- Reduction
- Dephosphorylation
Research Areas
- Apoptosis
- Cancer
- Caspases
- Cell Biology
- Ubiquitin Proteasome Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CASP7
bosterbio.com/bosterbio-gene-info-cards/CASP7
References
PMID: 8521391 by Fernandes-Alnemri T., et al. Mch3, a novel human apoptotic cysteine protease highly related to CPP32.
PMID: 8576161 by Duan H., et al. ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis.
4 Publications of Boster Caspase-7 Antibodies & ELISA Kits
- PubMed ID: 10.1002/ptr.5241, Isoflavones Extracted from Chickpea Cicer arietinum L. Sprouts Induce Mitochondr...
- PubMed ID: 28716756, Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis...
- PubMed ID: 28643466, Anemonin attenuates osteoarthritis progression through inhibiting the activation...
- PubMed ID: 22139054, Rasul A, Yu B, Khan M, Zhang K, Iqbal F, Ma T, Yang H. Int J Oncol. 2012 Apr;40(...
*More publications can be found for each product on its corresponding product page