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- Table of Contents
Caspase-7 Antibodies
AND CASP7 ELISA kits, Caspase-7 Proteins
Many biological assays use antibodies to detect Caspase-7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Caspase-7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Caspase-7 antibodies...
Designing a Western blot for Caspase-7? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CASP7 Western Blot GuideCASP7 Infographic by Boster Bio
All CASP7 Products
Product
Figures
Specificity
Applications
Price
Anti-Caspase-7/CASP7 Antibody Picoband®
1 Citations
Human, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01044-2
100 μg/vial
Cat # A01044-2
100 μg/vial
Anti-Cleaved-Caspase-7 (S199) CASP7 Antibody
1 Citations
Human, Mouse
ELISA, IF, IHC, WB
$380
Cat # A01044S199
100ul
Cat # A01044S199
100ul
CASP7 Overview
Facts about Caspase-7.
Caspase-7 (CASP7)
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs).
Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) in a'216-Asp-.
Gene Information
| Human | |
|---|---|
| Gene Name: | CASP7 |
| Uniprot: | P55210 |
| Entrez: | 840 |
Family
| Belongs to: |
|---|
| peptidase C14A family |
Alternative Names
apoptosis-related cysteine protease; Apoptotic protease Mch-3; CASP7; CASP-7; caspase 7, apoptosis-related cysteine peptidase; Caspase7; Caspase-7; EC 3.4.22; EC 3.4.22.60; ICE-like apoptotic protease 3; Lice2 alpha/beta/gamma; Mch3
Molecular Weight
Mass (kDA):
34.277 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q25.3 |
| Sequence: | 10; NC_000010.11 (113679162..113730909) |
Tissue Specificity
Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Leukemia
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Malignant Neoplasm Of Lung
- Lung Neoplasms
- Prostatic Neoplasms
- Adenocarcinoma
- Inflammation
- Malignant Neoplasm Of Prostate
Interacting Proteins
- BIRC2
- NIF3L1
- PAK2
- SAT1
- SMPD1
- XIAP
Pathways
- Cell Death
- Induction Of Apoptosis
- Cell Cycle
- Proteolysis
- Cell Proliferation
- Cell Growth
- Programmed Cell Death
- Apoptotic Process
- Localization
- Pathogenesis
- Cell Cycle Arrest
- Secretion
- Sensitization
PTMs
- Cleavage
- Phosphorylation
- Ubiquitination
- Reduction
- Dephosphorylation
Research Areas
- Apoptosis
- Cancer
- Caspases
- Cell Biology
- Ubiquitin Proteasome Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CASP7
bosterbio.com/bosterbio-gene-info-cards/CASP7
References
PMID: 8521391 by Fernandes-Alnemri T., et al. Mch3, a novel human apoptotic cysteine protease highly related to CPP32.
PMID: 8576161 by Duan H., et al. ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis.
4 Publications of Boster Caspase-7 Antibodies & ELISA Kits
- PubMed ID: 10.1002/ptr.5241, Isoflavones Extracted from Chickpea Cicer arietinum L. Sprouts Induce Mitochondr...
- PubMed ID: 28716756, Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis...
- PubMed ID: 28643466, Anemonin attenuates osteoarthritis progression through inhibiting the activation...
- PubMed ID: 22139054, Rasul A, Yu B, Khan M, Zhang K, Iqbal F, Ma T, Yang H. Int J Oncol. 2012 Apr;40(...
*More publications can be found for each product on its corresponding product page