Coiled-coil domain-containing protein 8 (CCDC8)

Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is uncertain how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696).

Required for localization of CUL7 to the centrosome (PubMed:24793695). .