Centriolar coiled-coil protein of 110 kDa (CCP110)

Necessary for centrosome duplication at different phases of procentriole formation. Acts as a key negative regulator of ciliogenesis in cooperation with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064).

Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the combination of recycling endosomes to basal bodies during cilia formation (By similarity).