CCR10 Antibodies

AND CCR10 ELISA kits, CCR10 Proteins

Many biological assays use antibodies to detect CCR10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CCR10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CCR10 antibodies...

We validate the specificity of these antibodies to CCR10 by testing them on tissues known to express CCR10 positively and negatively. Browse below to find the CCR10 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CCR10 Infographic by Boster Bio

All CCR10 Products

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Anti-GPR2/CCR10 Antibody Picoband®

1 Q&As

Anti-GPR2/CCR10 antibody, PA1491, Western blottingLane 1: HELA Cell LysateLane 2: SW620 Cell LysateLane 3: A549 Cell LysateLane 4: MM231 Cell LysateLane 5: SMMC Cell Lysate

Human, Mouse, Rat

$370
Cat # PA1491
100 μg/vial

Anti-GPR2/CCR10 Antibody Picoband®

Western blot analysis of CCR10 using anti-CCR10 antibody (A04731-1)

IHC analysis of CCR10 using anti-CCR10 antibody (A04731-1)

Human, Mouse, Rat

IHC, WB

$370
Cat # A04731-1
100 μg/vial

CCR10 (NM_016602) Human Over-expression Lysate

Human

$628
Cat # LS002826
20 µg, 100 µg

CCR10 Overview

Facts about C-C chemokine receptor type 10.

CCR10 3D structure. Source: alphafold

C-C chemokine receptor type 10 (CCR10)

Receptor for chemokines SCYA27 and SCYA28.
Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis at a pre-B line.

Gene Information

Human
Gene Name:	CCR10
Uniprot:	P46092
Entrez:	2826

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

CC chemokine receptor 10; C-C chemokine receptor type 10; C-C CKR-10; CC-CKR-10; CCR10; CCR-10; chemokine (C-C motif) receptor 10; G protein-coupled receptor 2; GPR2; GPR2G-protein coupled receptor 2

Molecular Weight

Mass (kDA):
38.416 kDA

Genomic Context


Human

Location:	17q21.2
Sequence:	17; NC_000017.11 (42678889..42681843, complement)

Tissue Specificity

Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Inflammation
Cholangiocarcinoma
Dermatitis
Neoplasms
Tissue Adhesions
Skin Neoplasms
Neoplasm Metastasis
Dermatologic Disorders
Dermatitis, Atopic
Malignant Neoplasms
Melanoma
Lymphoma
Malignant Paraganglionic Neoplasm

Lymphoma, T-cell, Cutaneous
T-cell Lymphoma
Psoriasis
Dermatitis, Allergic Contact
Mycoses
Mycosis Fungoides
Contact Dermatitis

Interacting Proteins

ANXA2
S100A10

Pathways

Pathogenesis
Localization
Chemotaxis
Secretion
Cell Adhesion
Immune Response
Hypersensitivity
Angiogenesis
Cell Proliferation
Lactation
Regeneration
Wound Healing
Lymphocyte Migration

Cytokine Production
Cell Migration
Tropism
Cell Motility
Cytokine Secretion
Inflammatory Response
Leukocyte Migration

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCR10

References

PMID: 10725696 by Jarmin D.I., et al. Identification of the orphan receptor G-protein-coupled receptor 2 as CCR10, a specific receptor for the chemokine ESkine.

PMID: 10725697 by Homey B., et al. The orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC).