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- Table of Contents
CDKN3 Antibodies
AND CDKN3 ELISA kits, CDKN3 Proteins
Many biological assays use antibodies to detect CDKN3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CDKN3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CDKN3 antibodies...
Designing a Western blot for CDKN3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CDKN3 Western Blot GuideCDKN3 Infographic by Boster Bio
All CDKN3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1837
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1837
1 kit, containing one 96-well plate and all necessary reagents
CDKN3 Overview
Facts about Cyclin-dependent kinase inhibitor 3.
Cyclin-dependent kinase inhibitor 3 (CDKN3)
May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
Dephosphorylates CDK2 at'Thr-160' at a cyclin-dependent method. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CDKN3 |
| Uniprot: | Q16667 |
| Entrez: | 1033 |
Family
| Belongs to: |
|---|
| protein-tyrosine phosphatase family |
Alternative Names
CDI1KAP1; CDK2-associated dual specificity phosphatase; CDK2-associated dual-specificity phosphatase; Cdk-associated protein phosphatase; CIP2; cyclin-dependent kinase inhibitor 3; cyclin-dependent kinase interacting protein 2; Cyclin-dependent kinase interactor 1; Cyclin-dependent kinase-interacting protein 2; EC 3.1.3.16; EC 3.1.3.48; FLJ25787; KAPMGC70625; Kinase-associated phosphatase
Molecular Weight
Mass (kDA):
23.805 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q22.2 |
| Sequence: | 14; NC_000014.9 (54396868..54420218) |
Subcellular Localizations
Cytoplasm, perinuclear region.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Liver Neoplasms
- Liver Carcinoma
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Cell Transformation, Neoplastic
- Choline Deficiency
- Neoplasm Invasiveness
- Hepatitis
Interacting Proteins
- CDK2
Pathways
- Cell Cycle
- Cell Proliferation
- Dna Methylation
- Methylation
- Cell Cycle Arrest
- Cell Division
- Translation
- Cell Growth
- Rna Interference
- Programmed Cell Death
- Cell Cycle Phase
- Brain Development
- Immune Response
PTMs
- Dephosphorylation
- Phosphorylation
Research Areas
- Cell Cycle and Replication
- Core ESC-Like Genes
- Protein Phosphatase
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CDKN3
bosterbio.com/bosterbio-gene-info-cards/CDKN3
References
PMID: 8242750 by Gyuris J., et al. Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2.
PMID: 8127873 by Hannon G.J., et al. KAP: a dual specificity phosphatase that interacts with cyclin- dependent kinases.