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- Table of Contents
CELSR3 Antibodies
AND CELSR3 ELISA kits, CELSR3 Proteins
Many biological assays use antibodies to detect CELSR3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CELSR3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CELSR3 antibodies...
Designing an IHC experiment for CELSR3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CELSR3 IHC GuideCELSR3 Infographic by Boster Bio
All CELSR3 Products
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Specificity
Applications
Price
CELSR3 Overview
Facts about Cadherin EGF LAG seven-pass G-type receptor 3.
Cadherin EGF LAG seven-pass G-type receptor 3 (CELSR3)
Receptor that may have an important role in cell/cell signaling during nervous system formation. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CELSR3 |
| Uniprot: | Q9NYQ7 |
| Entrez: | 1951 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 2 family |
Alternative Names
Cadherin family member 11; cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila); CDHF11; CDHF11RESDA1; CELSR3; EGFL1; EGFL1cadherin EGF LAG seven-pass G-type receptor 3; EGF-like protein 1; EGF-like-domain, multiple 1; epidermal growth factor-like 1; Epidermal growth factor-like protein 1; Flamingo homolog 1; FMI1anchor protein; HFMI1; KIAA0812; MEGF2; MEGF2cadherin EGF LAG seven-pass G-type receptor 3, flamingo (Drosophila) homolog; multiple EGF-like domains 2; Multiple EGF-like domains protein 2; Multiple epidermal growth factor-like domains protein 2; RESDA1
Molecular Weight
Mass (kDA):
358.185 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p21.31 |
| Sequence: | 3; NC_000003.12 (48636463..48662886, complement) |
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinogenesis
- Nervousness
- Malignant Neoplasm Of Pancreas
- Tissue Adhesions
- Neoplasm Metastasis
- Malignant Neoplasm Of Lung
- Pancreatitis
- Fibrosis
- Pancreatic Neoplasm
- Colorectal Cancer
- Cell Invasion
Interacting Proteins
- NCK1
Pathways
- Neural Tube Closure
- Gastrulation
- Tube Closure
- Convergent Extension
- Localization
- Cell Adhesion
- Brain Development
- Neurogenesis
- Initiation Of Neural Tube Closure
- Jun Phosphorylation
- Somitogenesis
- Spermatogenesis
- Cell Maturation
PTMs
Research Areas
- GPCR
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CELSR3
bosterbio.com/bosterbio-gene-info-cards/CELSR3
References
PMID: 10716726 by Wu Q., et al. Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.
PMID: 9693030 by Nakayama M., et al. Identification of high-molecular-weight proteins with multiple EGF- like motifs by motif-trap screening.