Chitinase-3-like protein 1 (CHI3L1)

Carbohydrate-binding lectin with a taste for chitin. Has no chitinase activity.

May play a role in tissue remodeling and in the capacity of cells to react to and cope with changes in their surroundings. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation.