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- Table of Contents
Clec7a Antibodies
AND Clec7a ELISA kits, Clec7a Proteins
Many biological assays use antibodies to detect Clec7a, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Clec7a in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Clec7a antibodies...
Designing a Western blot for Clec7a? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CLEC7A Western Blot GuideClec7a Infographic by Boster Bio
All Clec7a Products
Product
Figures
Specificity
Applications
Price
Mouse
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A02731-1
100 μg/vial
Cat # A02731-1
100 μg/vial
Human
ELISA, Flow Cytometry, WB
$370
Cat # A02731-2
100 μg/vial
Cat # A02731-2
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M02731
100 μg
Cat # M02731
100 μg
Clec7a Overview
Facts about C-type lectin domain family 7 member A.
C-type lectin domain family 7 member A (Clec7a)
Lectin that functions as routine receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for its TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B.
Improves cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Clec7a |
| Uniprot: | Q6QLQ4 |
| Entrez: | 56644 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Beta-glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; Dectin1; Dectin-1; DECTIN1CANDF4; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; hDectin-1; lectin-like receptor 1
Molecular Weight
Mass (kDA):
27.42 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 6|6 F3 |
| Sequence: | 6; |
Tissue Specificity
Detected in spleen (at protein level). Highly expressed in dendritic cells, spleen and thymus. Detected in epidermal Langerhans cells. Detected in macrophages, liver and lung.
Diseases
- Inflammation
- Dermatitis
- Infective Disorder
- Histoplasmosis
- Influenza
- Psoriasis
- Influenza Due To Influenza A Virus Subtype H1n1
- Dermatitis, Atopic
- Inflammatory Bowel Diseases
- Endometrial Polyp
- Intestinal Diseases
- Ulcerative Colitis
Pathways
- Immune Response
- Cytokine Production
- Phagocytosis
- Tissue Remodeling
- Innate Immune Response
- Aging
- Cytokine Secretion
- Proteolysis
PTMs
- Disulfide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Clec7a
bosterbio.com/bosterbio-gene-info-cards/Clec7a
References
PMID: 10779524 by Ariizumi K., et al. Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning.
PMID: 11544516 by Brown G.D., et al. Immune recognition. A new receptor for beta-glucans.