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- Table of Contents
Facts about C-type lectin domain family 7 member A.
Improves cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell.
Mouse | |
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Gene Name: | Clec7a |
Uniprot: | Q6QLQ4 |
Entrez: | 56644 |
Belongs to: |
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No superfamily |
Beta-glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; Dectin1; Dectin-1; DECTIN1CANDF4; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; hDectin-1; lectin-like receptor 1
Mass (kDA):
27.42 kDA
Mouse | |
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Location: | 6|6 F3 |
Sequence: | 6; |
Detected in spleen (at protein level). Highly expressed in dendritic cells, spleen and thymus. Detected in epidermal Langerhans cells. Detected in macrophages, liver and lung.
PMID: 10779524 by Ariizumi K., et al. Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning.
PMID: 11544516 by Brown G.D., et al. Immune recognition. A new receptor for beta-glucans.