Calponin-2 Antibodies

AND CNN2 ELISA kits, Calponin-2 Proteins

Many biological assays use antibodies to detect Calponin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Calponin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Calponin-2 antibodies...

We validate the specificity of these antibodies to Calponin-2 by testing them on tissues known to express CNN2 positively and negatively. Browse below to find the CNN2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Calponin-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the CNN2 Western Blot Guide

Designing an IHC experiment for Calponin-2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the CNN2 IHC Guide

CNN2 Infographic by Boster Bio

All CNN2 Products

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Product

Figures

Specificity

Applications

Price

Anti-Calponin 2/CNN2 Antibody Picoband®

Western blot analysis of Calponin 2/CNN2 using anti-Calponin 2/CNN2 antibody (A08680-2)

IHC analysis of Calponin 2/CNN2 using anti-Calponin 2/CNN2 antibody (A08680-2)

Flow Cytometry analysis of Daudi cells using anti-Calponin 2/CNN2 antibody (A08680-2)

Human

Flow Cytometry, IHC, WB

$370
Cat # A08680-2
100 μg/vial

CNN2 (NM_004368) Human Over-expression Lysate

CNN2 Human Over-expression Lysates NM_004368

Human

$628
Cat # LS001265
20 µg, 100 µg

Anti-Calponin Cnn2 Antibody (Monoclonal, 35C58)

Chicken, Human, Turkey

IHC, ICC, WB

$370
Cat # M08680-2
100 μg/vial

CNN2 (NM_201277) Human Recombinant Protein

Coomassie blue staining of purified CNN2 protein

$1062
Cat # PROTQ99439
20 µg

CNN2 Overview

Facts about Calponin-2.

CNN2 3D structure. Source: alphafold

Calponin-2 (CNN2)

Lean filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It's capable of binding to actin, calmodulin, troponin C and tropomyosin.

The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. .

Gene Information

Human
Gene Name:	CNN2
Uniprot:	Q99439
Entrez:	1265

Family

Belongs to:

calponin family

Alternative Names

calponin 2; Calponin H2, smooth muscle; calponin-2; Neutral calponin

Molecular Weight

Mass (kDA):
33.697 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (1026608..1039065)

Tissue Specificity

Heart and smooth muscle.

Diseases

Malignant Neoplasms
Carcinogenesis
Carcinoma
Neoplasms
Tissue Adhesions
Keratosis
Squamous Cell Carcinoma Of Skin
Melanoma
Hypoxia
Pre-eclampsia
Edema
Tumor Angiogenesis

Anoxia
Microcephaly
Rectal Carcinoma
Primary Microcephaly
Malignant Squamous Cell Neoplasm
Skin Neoplasms
Malignant Neoplasm Of Skin

Pathways

Natural Killer Cell Mediated Cytotoxicity
Cell Migration
Diapedesis
Mitosis
Dna Repair
Immune Response
Neurogenesis
Cell Fate Determination
Cell Cycle Arrest
Endothelial Cell Migration
Reverse Transcription
Urea Cycle
Translation

Phagocytosis
Cell Cycle
Cell Motility
Antigen Processing And Presentation
Interphase
Angiogenesis
Wound Healing

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CNN2

References

PMID: 8889829 by Masuda H., et al. Molecular cloning and characterization of human non-smooth muscle calponin.

PMID: 9001224 by Kuromitsu J., et al. A unique downregulation of h2-calponin gene expression in Down syndrome: a possible attenuation mechanism for fetal survival by methylation at the CpG island in the trisomic chromosome 21.