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- Table of Contents
CR2 Antibodies
AND CR2 ELISA kits, CR2 Proteins
Many biological assays use antibodies to detect CR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CR2 antibodies...
Designing a Western blot for CR2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CR2 Western Blot GuideDesigning an IHC experiment for CR2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CR2 IHC GuideCR2 Infographic by Boster Bio
All CR2 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # FEK1315
96 wells/kit, with removable strips.
Cat # FEK1315
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01632-2
20μL, 40μL, 100μL, 200μL
Cat # M01632-2
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01632-3
100 μl/vial
Cat # M01632-3
100 μl/vial
Human, Mouse
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01632
100 μl
Cat # M01632
100 μl
CR2 Overview
Facts about Complement receptor type 2.
Complement receptor type 2 (CR2)
Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU (PubMed:7753047).
Participates in B lymphocytes activation (PubMed:7753047)..
Gene Information
| Human | |
|---|---|
| Gene Name: | CR2 |
| Uniprot: | P20023 |
| Entrez: | 1380 |
Family
| Belongs to: |
|---|
| receptors of complement activation (RCA) family |
Alternative Names
C3DR; C3DRSLEB9; CD21 antigen; CD21; Complement C3d receptor; complement component (3d/Epstein Barr virus) receptor 2; complement receptor type 2; CR2; EBV receptor; Epstein-Barr virus receptor
Molecular Weight
Mass (kDA):
112.916 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q32.2 |
| Sequence: | 1; NC_000001.11 (207454328..207489892) |
Tissue Specificity
Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Leukemia
- Leukemia, Myelocytic, Acute
- Acute Lymphocytic Leukemia
- Lymphoma
- Myeloid Leukemia
- Graft-vs-host Disease
- Neoplasms
- Malignant Neoplasms
- Lupus Erythematosus, Systemic
- Autoimmune Reaction
- Acute Gvh Disease
- Hiv Infections
- Burkitt Lymphoma
Pathways
- Complement Activation
- Immune Response
- Cell Activation
- B Cell Activation
- Pathogenesis
- Cell Proliferation
- Cell Cycle
- Humoral Immune Response
- Localization
- Cell Development
- Secretion
- B Cell Proliferation
- Glycosylation
PTMs
- Phosphorylation
- Cleavage
- Glycosylation
- Biotinylation
- Methylation
- Dephosphorylation
- Reduction
Research Areas
- Adaptive Immunity
- Apoptosis
- Dendritic Cell Markers
- Immunology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CR2
bosterbio.com/bosterbio-gene-info-cards/CR2
References
PMID: 2563370 by Fujisaku A., et al. Genomic organization and polymorphisms of the human C3d/Epstein-Barr virus receptor.
PMID: 2832506 by Weis J.J., et al. Structure of the human B lymphocyte receptor for C3d and the Epstein- Barr virus and relatedness to other members of the family of C3/C4 binding proteins.