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- Table of Contents
Cystatin-M Antibodies
AND CST6 ELISA kits, Cystatin-M Proteins
Many biological assays use antibodies to detect Cystatin-M, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cystatin-M in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cystatin-M antibodies...
Designing an IHC experiment for Cystatin-M? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CST6 IHC GuideCST6 Infographic by Boster Bio
All CST6 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1965
96 wells/kit, with removable strips.
Cat # EK1965
96 wells/kit, with removable strips.
Human
Flow Cytometry, IHC, IHC-F, ICC, WB
$370
Cat # M02794
100 μg/vial
Cat # M02794
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # M02833-1
100 μg/vial
Cat # M02833-1
100 μg/vial
Enzyme Activity, SDS-PAGE
$265
Cat # PROTP04080
Starting from 10ug
Cat # PROTP04080
Starting from 10ug
CST6 Overview
Facts about Cystatin-M.
Cystatin-M (CST6)
Shows moderate inhibition of cathepsin B but is not active against cathepsin C. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CST6 |
| Uniprot: | Q15828 |
| Entrez: | 1474 |
Family
| Belongs to: |
|---|
| cystatin family |
Alternative Names
CST6; cystatin 6; Cystatin E/M; cystatin M; cystatin M/E; Cystatin-6; cystatin-E; cystatin-M; cysteine proteinase inhibitor
Molecular Weight
Mass (kDA):
16.511 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q13.1 |
| Sequence: | 11; NC_000011.10 (66012008..66013505) |
Tissue Specificity
Restricted to the stratum granulosum of normal skin, the stratum granulosum/spinosum of psoriatic skin, and the secretory coils of eccrine sweat glands. Low expression levels are found in the nasal cavity.
Subcellular Localizations
Secreted.
Diseases
- Neoplasms
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Neoplasm Metastasis
- Carcinoma
- Cell Invasion
- Malignant Paraganglionic Neoplasm
- Neoplasm Invasiveness
- Primary Neoplasm
- Tumor Progression
- Ichthyoses
Pathways
- Methylation
- Localization
- Cell Proliferation
- Dna Methylation
- Cell Growth
- Cornification
- Gene Silencing
- Cell Migration
- Proteolysis
- Angiogenesis
- Cell Adhesion
- Cell Motility
- Bone Resorption
PTMs
- Methylation
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CST6
bosterbio.com/bosterbio-gene-info-cards/CST6
References
PMID: 8995380 by Sotiropoulou G., et al. Identification, cloning, and characterization of cystatin M, a novel cysteine proteinase inhibitor, down-regulated in breast cancer.
PMID: 9099741 by Ni J., et al. Cystatin E is a novel human cysteine proteinase inhibitor with structural resemblance to family 2 cystatins.