Cystatin-M Antibodies

AND CST6 ELISA kits, Cystatin-M Proteins

Many biological assays use antibodies to detect Cystatin-M, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cystatin-M in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cystatin-M antibodies...

We validate the specificity of these antibodies to Cystatin-M by testing them on tissues known to express CST6 positively and negatively. Browse below to find the CST6 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CST6 Infographic by Boster Bio

All CST6 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human Cystatin M/Cystatin E/CST6 ELISA Kit PicoKine®

8 Q&As

Human

ELISA

$499
Cat # EK1965
96 wells/kit, with removable strips.

Anti-Cystatin-M CST6 Antibody

Western blot (WB) analysis of CST6 polyclonal antibody at 1:500 dilution
Lane1:HEK293T whole cell lysate
Lane2:PC12 whole cell lysate

Human, Rat

$405
Cat # A07408
100ul

Anti-Cystatin E/M CST6 Antibody

Human

ELISA, IF, IHC

$380
Cat # A07408-1
100ul

CST6 (NM_001323) Human Recombinant Protein

Coomassie blue staining of purified CST6 protein

$1249
Cat # PROTQ15828
20 µg

CST6 (NM_001323) Human Over-expression Lysate

Human

$628
Cat # LS001474
20 µg, 100 µg

CST6 Overview

Facts about Cystatin-M.

CST6 3D structure. Source: alphafold

Cystatin-M (CST6)

Shows moderate inhibition of cathepsin B but is not active against cathepsin C. .

Gene Information

Human
Gene Name:	CST6
Uniprot:	Q15828
Entrez:	1474

Family

Belongs to:

cystatin family

Alternative Names

CST6; cystatin 6; Cystatin E/M; cystatin M; cystatin M/E; Cystatin-6; cystatin-E; cystatin-M; cysteine proteinase inhibitor

Molecular Weight

Mass (kDA):
16.511 kDA

Genomic Context


Human

Location:	11q13.1
Sequence:	11; NC_000011.10 (66012008..66013505)

Tissue Specificity

Restricted to the stratum granulosum of normal skin, the stratum granulosum/spinosum of psoriatic skin, and the secretory coils of eccrine sweat glands. Low expression levels are found in the nasal cavity.

Subcellular Localizations

Secreted.

Diseases

Neoplasms
Malignant Neoplasms
Malignant Neoplasm Of Breast
Mammary Neoplasms
Neoplasm Metastasis
Carcinoma
Cell Invasion
Malignant Paraganglionic Neoplasm
Neoplasm Invasiveness
Primary Neoplasm
Tumor Progression
Ichthyoses

Carcinoma Breast Stage Iv
Ductal Carcinoma
Cell Transformation, Neoplastic
Metastatic Malignant Neoplasm To The Lymph Node
Tumor Angiogenesis
Tissue Adhesions
Lymphatic Metastasis

Pathways

Methylation
Localization
Cell Proliferation
Dna Methylation
Cell Growth
Cornification
Gene Silencing
Cell Migration
Proteolysis
Angiogenesis
Cell Adhesion
Cell Motility
Bone Resorption

Transport
Keratinization
Dna Hypermethylation
Negative Regulation Of Centriole Replication
Negative Regulation Of Wnt Receptor Signaling Pathway
Immune Response
Hypersensitivity

PTMs

Methylation
Glycosylation

Biotinylation
Demethylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CST6

References

PMID: 8995380 by Sotiropoulou G., et al. Identification, cloning, and characterization of cystatin M, a novel cysteine proteinase inhibitor, down-regulated in breast cancer.

PMID: 9099741 by Ni J., et al. Cystatin E is a novel human cysteine proteinase inhibitor with structural resemblance to family 2 cystatins.