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- Table of Contents
CUX1 Antibodies
AND CUX1 ELISA kits, CUX1 Proteins
Many biological assays use antibodies to detect CUX1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CUX1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CUX1 antibodies...
Designing an IHC experiment for CUX1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CUX1 IHC GuideCUX1 Infographic by Boster Bio
All CUX1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01653-4
100 μg/vial
Cat # A01653-4
100 μg/vial
CUX1 Overview
Facts about Homeobox protein cut-like 1.
Homeobox protein cut-like 1 (CUX1)
Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters.
Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer.
Gene Information
| Human | |
|---|---|
| Gene Name: | CUX1 |
| Uniprot: | P39880 |
| Entrez: | 1523 |
Family
| Belongs to: |
|---|
| CUT homeobox family |
Alternative Names
CASP; CCAAT displacement protein; CDP; CDP/Cux; CDPCCAAT displacement protein; COY1; cut (Drosophila)-like 1 (CCAAT displacement protein); CUT; CUTL1; cut-like 1, CCAAT displacement protein (Drosophila); cut-like homeobox 1; CUX; CUX1; FLJ31745; golgi integral membrane protein 6; GOLIM6; homeobox protein cut-like 1; Homeobox protein cux-1; Nbla10317; p100; p110; p200; p75; protein CASP; putative protein product of Nbla10317
Molecular Weight
Mass (kDA):
164.187 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q22.1 |
| Sequence: | 7; NC_000007.14 (101815991..102283958) |
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Malignant Neoplasms
- Cell Invasion
- Mammary Neoplasms
- Leukemia
- Malignant Neoplasm Of Breast
- Neoplasm Metastasis
- Neoplasm Invasiveness
- Carcinoma
- Kidney Diseases
- Tumor Progression
- Fibroid Tumor
- Myeloid Leukemia
Pathways
- Cell Cycle
- S Phase
- Cell Proliferation
- Dna Replication
- Cell Migration
- Mitosis
- Cell Motility
- Localization
- Cell Growth
- Cell Differentiation
- Cell Death
- Cytokinesis
- Cell Division
PTMs
- Phosphorylation
- Cleavage
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CUX1
bosterbio.com/bosterbio-gene-info-cards/CUX1
References
PMID: 1301999 by Neufeld E.J., et al. Human CCAAT displacement protein is homologous to the Drosophila homeoprotein, cut.
PMID: 9799793 by Gloeckner G., et al. Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes.