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- Table of Contents
CYP17A1 Antibodies
AND CYP17A1 ELISA kits, CYP17A1 Proteins
Many biological assays use antibodies to detect CYP17A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CYP17A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CYP17A1 antibodies...
Designing a Western blot for CYP17A1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CYP17A1 Western Blot GuideCYP17A1 Infographic by Boster Bio
All CYP17A1 Products
Product
Figures
Specificity
Applications
Price
Mouse, Rat
ELISA, IF, IHC, WB
$370
Cat # A00615-3
100 μg/vial
Cat # A00615-3
100 μg/vial
Human, Rat
Flow Cytometry, IHC, WB
$370
Cat # A00615-1
100 μg/vial
Cat # A00615-1
100 μg/vial
Human
Flow Cytometry, IHC, WB
$523
Cat # M00615
100 µl
Cat # M00615
100 µl
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00615-1
100 μl/vial
Cat # M00615-1
100 μl/vial
Human
ELISA
$480
Cat # EKC1905
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1905
1 kit, containing one 96-well plate and all necessary reagents
Human
$628
Cat # LS001586
20 µg, 100 µg
Cat # LS001586
20 µg, 100 µg
CYP17A1 Overview
Facts about Steroid 17-alpha-hydroxylase/17,20 lyase.
Steroid 17-alpha-hydroxylase/17,20 lyase (CYP17A1)
Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated goods and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.
Involved in sexual development during fetal life and at puberty. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CYP17A1 |
| Uniprot: | P05093 |
| Entrez: | 1586 |
Family
| Belongs to: |
|---|
| cytochrome P450 family |
Alternative Names
CPT7; cyp17; CYP17A1; cytochrome p450 XVIIA1; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenalhyperplasia; Cytochrome P450c17; Cytochrome P450-C17; EC 1.14.99; P450C17; P450C17CYPXVII; S17AH
Molecular Weight
Mass (kDA):
57.371 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q24.32 |
| Sequence: | 10; NC_000010.11 (102830531..102837413, complement) |
Subcellular Localizations
Endoplasmic reticulum membrane. Microsome membrane.
Diseases
- Malignant Neoplasms
- Congenital Adrenal Hyperplasia
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Neoplasms
- Hypertensive Disease
- Hyperplasia
- Adrenal Hyperplasia
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Polycystic Ovary Syndrome
- Virilism
Pathways
- Secretion
- Pathogenesis
- Cell Proliferation
- Transport
- Ovulation
- Spermatogenesis
- Methylation
- Dna Methylation
- Aging
- Cell Differentiation
- Mating
- Menstruation
- Cholesterol Transport
PTMs
- Cleavage
- Phosphorylation
- Methylation
- Hydroxylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP17A1
bosterbio.com/bosterbio-gene-info-cards/CYP17A1
References
PMID: 3025870 by Chung B.-C., et al. Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues.
PMID: 3500022 by Picado-Leonard J., et al. Cloning and sequence of the human gene for P450c17 (steroid 17 alpha- hydroxylase/17,20 lyase): similarity with the gene for P450c21.
2 Publications of Boster CYP17A1 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.fct.2017.01.011, Effects of six priority controlled phthalate esters with long-term low-dose inte...
- PubMed ID: 24212501, Liu C, Luan X, He Y, Xia X, Sun L, Miao W, Jin Y, Liu L. Biomed Microdevices. 20...
*More publications can be found for each product on its corresponding product page