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- Table of Contents
Cytochrome P450 3A5 Antibodies
AND CYP3A5 ELISA kits, Cytochrome P450 3A5 Proteins
Many biological assays use antibodies to detect Cytochrome P450 3A5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 3A5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 3A5 antibodies...
Designing a Western blot for Cytochrome P450 3A5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CYP3A5 Western Blot GuideCYP3A5 Infographic by Boster Bio
All CYP3A5 Products
Product
Figures
Specificity
Applications
Price
Human
$628
Cat # LS001577
20 µg, 100 µg
Cat # LS001577
20 µg, 100 µg
CYP3A5 Overview
Facts about Cytochrome P450 3A5.
Cytochrome P450 3A5 (CYP3A5)
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.
It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CYP3A5 |
| Uniprot: | P20815 |
| Entrez: | 1577 |
Family
| Belongs to: |
|---|
| cytochrome P450 family |
Alternative Names
aryl hydrocarbon hydroxylase; CP35; CYPIIIA5; cytochrome P450 3A5; Cytochrome P450 HLp2; cytochrome P-450; cytochrome P450, family 3, subfamily A, polypeptide 5; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5; Cytochrome P450-PCN3; DKFZp686L16231; EC 1.14.14.1; flavoprotein-linked monooxygenase; microsomal monooxygenase; niphedipine oxidase; P450PCN3FLJ31317; PCN3; xenobiotic monooxygenase
Molecular Weight
Mass (kDA):
57.109 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q22.1 |
| Sequence: | 7; NC_000007.14 (99648194..99679996, complement) |
Subcellular Localizations
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Breast
- Hiv Infections
- Mammary Neoplasms
- Hypertensive Disease
- Leukemia
- Cholangiocarcinoma
- Carcinoma
- Dysequilibrium Syndrome
- Malignant Neoplasm Of Prostate
- Decreased Immunologic Activity [pe]
Pathways
- Transport
- Excretion
- Glomerular Filtration
- Platelet Aggregation
- Drug Resistance
- Drug Transport
- Localization
- Pathogenesis
- Demethylation
- Conjugation
- Dna Repair
- Immune Response
- Reverse Transcription
PTMs
- Hydroxylation
- Oxidation
- Demethylation
- Phosphorylation
- Cleavage
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP3A5
bosterbio.com/bosterbio-gene-info-cards/CYP3A5
References
PMID: 2802615 by Schuetz J.D., et al. Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver.
PMID: 11266076 by Gellner K., et al. Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene.