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- Table of Contents
Cyclin-A2 Antibodies
AND CCNA2 ELISA kits, Cyclin-A2 Proteins
Many biological assays use antibodies to detect Cyclin-A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cyclin-A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cyclin-A2 antibodies...
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CCNA2 Infographic by Boster Bio
All CCNA2 Products
Product
Figures
Specificity
Applications
Price
Anti-Cyclin A2/CCNA2 Antibody Picoband®
6 Citations 1 Q&As
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9424
100 μg/vial
Cat # PB9424
100 μg/vial
Anti-Cyclin A Ccna2 Antibody (Monoclonal, CY-A1)
12 Citations 6 Q&As
Bovine, Human, Mouse
ICC, WB
$370
Cat # MA1032
100 μg/vial
Cat # MA1032
100 μg/vial
Anti-Cyclin A2 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00700-1
100 μl
Cat # M00700-1
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00700-3
20μL, 40μL, 100μL, 200μL
Cat # M00700-3
20μL, 40μL, 100μL, 200μL
CCNA2 Overview
Facts about Cyclin-A2.
Cyclin-A2 (CCNA2)
Cyclin which controls both the G1/S and the G2/M transition stages of the cell cycle. Functions through the formation of particular serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2.
The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 through the cell cycle. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CCNA2 |
| Uniprot: | P20248 |
| Entrez: | 890 |
Family
| Belongs to: |
|---|
| cyclin family |
Alternative Names
CCN1CCNAcyclin-A; CCNA; CCNA2; Cyclin A2; Cyclin-A; cyclin-A2
Molecular Weight
Mass (kDA):
48.551 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q27 |
| Sequence: | 4; NC_000004.12 (121816444..121823883, complement) |
Subcellular Localizations
Nucleus. Cytoplasm. Exclusively nuclear during interphase (PubMed:1312467). Detected in the nucleus and the cytoplasm at prophase (PubMed:1312467). Cytoplasmic when associated with SCAPER (PubMed:17698606).
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Cell Transformation, Neoplastic
- Leukemia
- Retinoblastoma
- Adenocarcinoma
- Liver Carcinoma
- Malignant Paraganglionic Neoplasm
- Hyperplasia
- Malignant Neoplasm Of Lung
Interacting Proteins
- AKT1
- CDK2
- CDKN1A
- CDKN1B
- UHRF2
Pathways
- Cell Cycle
- Cell Proliferation
- Mitosis
- S Phase
- Cell Division
- Cell Cycle Arrest
- Regeneration
- Dna Replication
- Cell Growth
- Localization
- Rna Interference
- Spermatogenesis
- Hepatocyte Proliferation
PTMs
- Phosphorylation
- Methylation
- Sumoylation
Research Areas
- Cancer
- Cell Biology
- Cell Cycle and Replication
- Cellular Markers
- Core ESC-Like Genes
- Stem Cell Markers
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CCNA2
bosterbio.com/bosterbio-gene-info-cards/CCNA2
References
PMID: 1967822 by Wang J., et al. Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma.
PMID: 8202514 by Henglein B., et al. Structure and cell cycle-regulated transcription of the human cyclin A gene.
12 Publications of Boster Cyclin-A2 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.mce.2019.110697, LncRNA HCP5 promotes cell proliferation and inhibits apoptosis via miR-27a-3p/IG...
- PubMed ID: 10.1016/j.cbi.2017.07.020, Synergism between thioredoxin reductase inhibitor ethaselen and sodium selenite ...
- PubMed ID: 31974617, Wang S,Zhang C,Zhang X.Downregulation of long non‑coding RNA ANRIL promotes pr...
- PubMed ID: 24628936, Activin A induces growth arrest through a SMAD- dependent pathway in hepatic pro...
- PubMed ID: 28749992, Zhang C, Chang C, Zhao W, Gao H, Wang Q, Li D, Zhang F, Zhang S, Xu C,. PLoS One...
- PubMed ID: 28932249, Zhang C, Chang C, Li D, Zhang F, Xu C. Cell Mol Biol Lett. 2017 Sep 16;22:21. do...
- PubMed ID: 25918708, Wang C, Ge Q, Chen Z, Hu J, Li F, Song X, Xu H, Ye Z. Biomed Res Int. 2015;2015:...
- PubMed ID: 23337938, Mao F, Wang B, Xiao Q, Xi G, Sun W, Zhang H, Ye F, Wan F, Guo D, Lei T, Chen X. ...
- PubMed ID: 20878477, Lin P, Fu J, Zhao B, Lin F, Zou H, Liu L, Zhu C, Wang H, Yu X. Mol Biol Rep. 201...
- PubMed ID: 24076388, Deng L, Lu Y, Zhao X, Sun Y, Shi Y, Fan H, Liu C, Zhou J, Nie Y, Wu K, Fan D, Gu...
- PubMed ID: 25151579, Zhao P, Li Y, Gao G, Wang S, Yan Y, Zhan X, Liu Z, Mao Z, Chen S, Wang L. Eur J ...
- PubMed ID: 24194897, Li M, Tian L, Wang L, Yao H, Zhang J, Lu J, Sun Y, Gao X, Xiao H, Liu M. Plos On...
*More publications can be found for each product on its corresponding product page