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- Table of Contents
CD163 Antibodies
AND CD163 ELISA kits, CD163 Proteins
Many biological assays use antibodies to detect CD163, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD163 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD163 antibodies...
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CD163 Infographic by Boster Bio
All CD163 Products
Product
Figures
Specificity
Applications
Price
Human CD163 / M130 ELISA Kit PicoKine®
2 Citations 9 Q&As
Human
ELISA
$499
Cat # EK0715
96 wells/kit, with removable strips.
Cat # EK0715
96 wells/kit, with removable strips.
Mouse CD163 ELISA Kit PicoKine®
4 Citations 7 Q&As
Mouse
ELISA
$499
Cat # EK1146
96 wells/kit, with removable strips.
Cat # EK1146
96 wells/kit, with removable strips.
Anti-CD163 Antibody Picoband®
3 Citations 17 Q&As
Human
ELISA, IHC, WB
$370
Cat # A00812-1
100 μg/vial
Cat # A00812-1
100 μg/vial
Human CD163/M130 PicoKine® Quick ELISA Kit
1 Citations 1 Q&As
Human
ELISA
$499
Cat # FEK0715
96 wells/kit, with removable strips.
Cat # FEK0715
96 wells/kit, with removable strips.
Human
IF, IHC, WB, LMNX
$523
Cat # M00812-2
100 µl
Cat # M00812-2
100 µl
Human
Flow Cytometry, IF, WB, LMNX
$523
Cat # M00812-3
100 µl
Cat # M00812-3
100 µl
Anti-Cd163 Antibody Picoband®
5 Citations
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00812-2
100 μg/vial
Cat # A00812-2
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00812-6
100 μg
Cat # M00812-6
100 μg
CD163 Overview
Facts about Scavenger receptor cysteine-rich type 1 protein M130.
Scavenger receptor cysteine-rich type 1 protein M130 (CD163)
Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and following breakdown of heme.
Binds hemoglobin/haptoglobin complexes at a calcium-dependent and pH-dependent method. Exhibits a greater affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype.
Gene Information
| Human | |
|---|---|
| Gene Name: | CD163 |
| Uniprot: | Q86VB7 |
| Entrez: | 9332 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD163 antigenscavenger receptor cysteine-rich type 1 protein M130; CD163 molecule; CD163; GHI/61; HbSR; Hemoglobin scavenger receptor; M130; M130macrophage-associated antigen; MM130; RM3/1
Molecular Weight
Mass (kDA):
125.451 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12p13.31 |
| Sequence: | 12; NC_000012.12 (7470811..7503818, complement) |
Tissue Specificity
Expressed in monocytes and mature macrophages such as Kupffer cells in the liver, red pulp macrophages in the spleen, cortical macrophages in the thymus, resident bone marrow macrophages and meningeal macrophages of the central nervous system. Expressed also in blood. Isoform 1 is the lowest abundant in the blood. Isoform 2 is the lowest abundant in the liver and the spleen. Isoform 3 is the predominant isoform detected in the blood.
Subcellular Localizations
[Soluble CD163]: Secreted.; Cell membrane; Single-pass type I membrane protein. Isoform 1 and isoform 2 show a lower surface expression when expressed in cells.
Diseases
- Inflammation
- Neoplasms
- Malignant Neoplasms
- Atherosclerosis
- Malignant Paraganglionic Neoplasm
- Sarcoma
- Hemolysis (disorder)
- Tissue Adhesions
- Neoplasm Metastasis
- Arthritis
- Carcinoma
- Inflammatory Response
- Porcine Reproductive And Respiratory Syndrome
Pathways
- Pathogenesis
- Macrophage Activation
- Secretion
- Immune Response
- Endocytosis
- Inflammatory Response
- Phagocytosis
- Angiogenesis
- Localization
- Cell Proliferation
- Cytokine Production
- Macrophage Differentiation
- Cell Adhesion
PTMs
- Phosphorylation
- Cleavage
- Oxidation
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD163
bosterbio.com/bosterbio-gene-info-cards/CD163
References
PMID: 8370408 by Law S.K.A., et al. A new macrophage differentiation antigen which is a member of the scavenger receptor superfamily.
PMID: 10403791 by Ritter M., et al. Genomic organization and chromosomal localization of the human CD163 (M130) gene: a member of the scavenger receptor cysteine-rich superfamily.
6 Publications of Boster CD163 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.bj.2020.09.004, Increased macrophage activation marker soluble CD163 is associated with graft dy...
- PubMed ID: 10.1016/j.biomaterials.2021.121323, Bioinspired design of mannose-decorated globular lysine dendrimers promotes diab...
- PubMed ID: -, ACS Appl.Bio Mater.2020,3,7,4335–4347 Publication Date:June 11,2020 https://do...
- PubMed ID: 32581565, Farag AGA,El Askary SA,Fathy WM,Elbassal F,Azzam AA,Tayel NR,Abdul Karim SS,Sheh...
- PubMed ID: 30323677, il-17 induces macrophages to M2-like phenotype via nF-%u03BAB
- PubMed ID: 27154032, SIV Infection Impairs the Central Nervous System in Chinese Rhesus Macaques
*More publications can be found for each product on its corresponding product page