This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
CD59 glycoprotein Antibodies
AND CD59 ELISA kits, CD59 glycoprotein Proteins
Many biological assays use antibodies to detect CD59 glycoprotein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD59 glycoprotein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD59 glycoprotein antibodies...
Designing a Western blot for CD59 glycoprotein? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CD59 Western Blot GuideCD59 Infographic by Boster Bio
All CD59 Products
Product
Figures
Specificity
Applications
Price
Anti-CPT1A Antibody Picoband®
4 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00917-3
100 μg/vial
Cat # A00917-3
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00938-2
100 μg/vial
Cat # M00938-2
100 μg/vial
Anti-Pannexin 1/PANX1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00915-2
100 μg/vial
Cat # A00915-2
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB, ELISA (Cap)
$370
Cat # M00961-1
100 μg/vial
Cat # M00961-1
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00914-2
100 μg/vial
Cat # M00914-2
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00951-1
100 μg/vial
Cat # M00951-1
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # RP1076
100 μg/vial
Cat # RP1076
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00949-2
100 μg/vial
Cat # M00949-2
100 μg/vial
Anti-CD59 Rabbit Monoclonal Antibody
1 Citations
Human
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M00914-1
100 μl
Cat # M00914-1
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00916-2
100 μg/vial
Cat # A00916-2
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # M00952
100 μg/vial
Cat # M00952
100 μg/vial
Human, Mouse
Flow Cytometry, IP, IHC-P, WB
$299
Cat # M00914-3
0.1 mg
Cat # M00914-3
0.1 mg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00914-6
100 μg
Cat # M00914-6
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00914-5
100 μg
Cat # M00914-5
100 μg
CD59 Overview
Facts about CD59 glycoprotein.
CD59 glycoprotein (CD59)
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 needed for complete formation of the osmolytic pore.
This inhibitor seems to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
Gene Information
| Human | |
|---|---|
| Gene Name: | CD59 |
| Uniprot: | P13987 |
| Entrez: | 966 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
16.3A5; 1F5 antigen; 1F5; 20 kDa homologous restriction factor; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16; CD59 antigen; CD59 antigen, complement regulatory protein; CD59 glycoprotein; CD59 molecule, complement regulatory protein; CD59; EJ16; EJ30; EJ30, EL32 and G344); EL32; FLJ38134; FLJ92039; G344; HRF20; HRF-20; human leukocyte antigen MIC11; Ly-6-like protein; lymphocytic antigen CD59/MEM43; MACIF; MAC-inhibitory protein; MAC-IP; MEM43 antigen; MEM43; membrane attack complex (MAC) inhibition factor; Membrane attack complex inhibition factor; Membrane in
Molecular Weight
Mass (kDA):
14.177 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p13 |
| Sequence: | 11; NC_000011.10 (33703010..33736479, complement) |
Subcellular Localizations
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Soluble form found in a number of tissues.
Diseases
- Paroxysmal Nocturnal Hemoglobinuria
- Hemoglobinuria
- Hemoglobinuria, Paroxysmal
- Hemolysis (disorder)
- Neoplasms
- Anemia
- Malignant Neoplasms
- Inflammation
- Aplastic Anemia
- Tissue Adhesions
- Leukemia
- Thrombosis
- Carcinoma
Interacting Proteins
- TMED2
Pathways
- Complement Activation
- Pathogenesis
- Cytolysis
- Cell Activation
- Immune Response
- Localization
- Cell Death
- Secretion
- Glycosylation
- Cell Proliferation
- T Cell Activation
- Complement-dependent Cytotoxicity
- Inflammatory Response
PTMs
- Glycosylation
- Cleavage
- Gpi Anchoring
- Phosphorylation
- Acylation
- Biotinylation
- Deamination
- Ubiquitination
Research Areas
- Cell Biology
- Cellular Markers
- Immunology
- Signal Transduction
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD59
bosterbio.com/bosterbio-gene-info-cards/CD59
References
PMID: 2475570 by Davies A., et al. CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.
PMID: 1689664 by Philbrick W.M., et al. The CD59 antigen is a structural homologue of murine Ly-6 antigens but lacks interferon inducibility.
5 Publications of Boster CD59 glycoprotein Antibodies & ELISA Kits
- PubMed ID: 22355243, Therapeutic efficacy of trehalose eye drops for treatment of murine dry eye indu...
- PubMed ID: 15378770, Down-modulation of heat shock protein 70 and up-modulation of Caspase-3 during s...
- PubMed ID: 26191239, Effects of intracerebral hemorrhage and subsequent minimally invasive hematoma a...
- PubMed ID: 23554704, Effects of minocycline on the expression of NGF and HSP70 and its neuroprotectio...
- PubMed ID: 17465496, Yi Sx, Peng Y, Chang Xr, Peng N, Yan J, Lin Yp. World J Gastroenterol. 2007 Apr ...
*More publications can be found for each product on its corresponding product page