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- Table of Contents
Chitotriosidase-1 Antibodies
AND CHIT1 ELISA kits, Chitotriosidase-1 Proteins
Many biological assays use antibodies to detect Chitotriosidase-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Chitotriosidase-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Chitotriosidase-1 antibodies...
Designing an IHC experiment for Chitotriosidase-1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the CHIT1 IHC GuideCHIT1 Infographic by Boster Bio
All CHIT1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK2032
96 wells/kit, with removable strips.
Cat # EK2032
96 wells/kit, with removable strips.
CHIT1 Overview
Facts about Chitotriosidase-1.
Chitotriosidase-1 (CHIT1)
Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens.
Isoform 3 has no enzymatic activity. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CHIT1 |
| Uniprot: | Q13231 |
| Entrez: | 1118 |
Family
| Belongs to: |
|---|
| glycosyl hydrolase 18 family |
Alternative Names
CHI3; CHIT1; CHITCHI3; chitinase 1 (chitotriosidase); chitinase-1; Chitotriosidase; chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
Molecular Weight
Mass (kDA):
51.681 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q32.1 |
| Sequence: | 1; NC_000001.11 (203216079..203229673, complement) |
Tissue Specificity
Detected in spleen. Secreted by cultured macrophages.
Subcellular Localizations
Secreted. Lysosome. A small proportion is lysosomal.
Diseases
- Asthma
- Gaucher Disease
- Malaria
- Malaria, Falciparum
- Mycoses
- Filariasis
- Infective Disorder
- Sclerosis
- Lung Diseases
- Neoplasms
- Gaucher Disease, Type 1
- Inflammation
- Filarial Elephantiases
Pathways
- Pathogenesis
- Immune Response
- Macrophage Activation
- Macrophage Differentiation
- Fermentation
- Sensitization
- Tissue Remodeling
- Cell Differentiation
PTMs
- Disulfide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHIT1
bosterbio.com/bosterbio-gene-info-cards/CHIT1
References
PMID: 7592832 by Boot R.G., et al. Cloning of a cDNA encoding chitotriosidase, a human chitinase produced by macrophages.
PMID: 7836450 by Renkema G.H., et al. Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins.