Chordin Antibodies

AND CHRD ELISA kits, Chordin Proteins

Many biological assays use antibodies to detect Chordin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Chordin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Chordin antibodies...

We validate the specificity of these antibodies to Chordin by testing them on tissues known to express CHRD positively and negatively. Browse below to find the CHRD antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHRD Infographic by Boster Bio

All CHRD Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Mouse Chordin ELISA Kit PicoKine®

7 Q&As

Mouse

ELISA

$499
Cat # EK1401
96 wells/kit, with removable strips.

Anti-Chordin CHRD Antibody

1 Q&As

Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200

Human, Mouse, Rat

ELISA, IF, IHC

$399
Cat # A05363
100μl

Rat Chordin ELISA Kit PicoKine®

10 Q&As

Rat Chordin PicoKine ELISA Kit Standard Curve

Rat

ELISA

$499
Cat # EK2086
96 wells/kit, with removable strips.

Chordin (CHRD) (NM_003741) Human Over-expression Lysate

Human

$960
Cat # LS008646
20 µg, 100 µg

Anti-Zebrafish Chordin/CHRD Antibody Picoband®

Western blot analysis of Chordin/CHRD using anti-Chordin/CHRD antibody (AZO57472)

Zebrafish

$470
Cat # AZO57472
100 μg/vial

CHRD Overview

Facts about Chordin.

CHRD 3D structure. Source: alphafold

Chordin (CHRD)

Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta household bone morphogenetic proteins (BMPs) and sequestering them in latent complexes (By similarity).

. .

Gene Information

Human
Gene Name:	CHRD
Uniprot:	Q9H2X0
Entrez:	8646

Family

Belongs to:

chordin family

Alternative Names

Chordin; CHRD; MGC133038; Sog

Molecular Weight

Mass (kDA):
102.032 kDA

Genomic Context


Human

Location:	3q27.1
Sequence:	3; NC_000003.12 (184380073..184390739)

Tissue Specificity

Expressed at the highest level in liver.

Subcellular Localizations

Secreted.

Diseases

Congenital Abnormality
Aneurysm
Dyslipidemias
Craniofacial Abnormalities
Hypercholesterolemia, Familial
Cornelia De Lange Syndrome
Neoplasm Invasiveness
Degenerative Polyarthritis
Fracture
Malignant Neoplasms
Neoplasms
Nervousness

Malignant Neoplasm Of Ovary
Ovarian Neoplasm
Bacterial Infections
Cartilage Injury
Cholecystolithiasis
Aortic Aneurysm

Interacting Proteins

BMP1
CATSPER1
HOXA1
KRTAP10-5
KRTAP10-7

KRTAP10-8
KRTAP10-9
KRTAP4-2
KRTAP5-9
KRTAP9-2

MEOX2
NOTCH2NL
OTX1
PLSCR1
SMAD3

SPRY2

Pathways

Gastrulation
Secretion
Cell Adhesion
Cell Proliferation
Flower Development
Osteoblast Differentiation
Photosynthesis
Zymogen Activation
Localization
Cartilage Development
Translation

Paracrine Signaling
Cell Death
Cell Motility
Forebrain Development
Neural Crest Formation

PTMs

Glycosylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHRD

References

PMID: 11472837 by Millet C., et al. The human chordin gene encodes several differentially expressed spliced variants with distinct BMP opposing activities.

PMID: 9782094 by Pappano W.N., et al. Coding sequence and expression patterns of mouse chordin and mapping of the cognate mouse chrd and human CHRD genes.