Dapper homolog 3 Antibodies

AND DACT3 ELISA kits, Dapper homolog 3 Proteins

Many biological assays use antibodies to detect Dapper homolog 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dapper homolog 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dapper homolog 3 antibodies...

We validate the specificity of these antibodies to Dapper homolog 3 by testing them on tissues known to express DACT3 positively and negatively. Browse below to find the DACT3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DACT3 Infographic by Boster Bio

All DACT3 Products

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Anti-Dapper homolog 3 Dact3 Antibody

Western blot analysis of Dact3 in rat brain tissue lysate with Dact3 antibody at 1 μg/mL

Human, Mouse, Rat

ELISA, WB

$481
Cat # A11557
0.1 mg

DACT3 (NM_145056) Human Over-expression Lysate

Human

$628
Cat # LS147906
20 µg, 100 µg

DACT3 Overview

Facts about Dapper homolog 3.

DACT3 3D structure. Source: alphafold

Dapper homolog 3 (DACT3)

May be involved in regulation of intracellular signaling pathways during evolution. Specifically believed to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins.

Gene Information

Human
Gene Name:	DACT3
Uniprot:	Q96B18
Entrez:	147906

Family

Belongs to:

dapper family

Alternative Names

Antagonist of beta-catenin Dapper homolog 3; arginine rich region 1; Arginine-rich region 1 protein; DACT3; Dapper 3; dapper homolog 3; dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis); MGC15476; RRR1

Molecular Weight

Mass (kDA):
64.949 kDA

Genomic Context


Human

Location:	19q13.32
Sequence:	19; NC_000019.10 (46647551..46661182, complement)

Diseases

Malignant Neoplasms
Neoplasms
Carcinogenesis
Neoplasm Metastasis
Tumor Progression
Malignant Neoplasm Of Breast
Malignant Neoplasm Of Lung
Carcinoma
Immunologic Deficiency Syndromes
Nervousness
Chronic Lymphocytic Leukemia/small Lymphocytic Lymphoma
Lymphoma

Papillary Thyroid Carcinoma
Mammary Neoplasms
Malignant Neoplasm Of Ovary
Epithelial Ovarian Cancer
Colorectal Cancer
Ovarian Neoplasm

Pathways

Methylation
Cell Cycle
Dna Methylation
Dna Repair
Segmentation
Pathogenesis

Histone Methylation

PTMs

Deacetylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DACT3

References

PMID: 16881060 by Fisher D.A., et al. Three Dact gene family members are expressed during embryonic development and in the adult brains of mice.

PMID: 18538736 by Jiang X., et al. DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.