This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
L-dopachrome tautomerase Antibodies
AND DCT ELISA kits, L-dopachrome tautomerase Proteins
Many biological assays use antibodies to detect L-dopachrome tautomerase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with L-dopachrome tautomerase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop L-dopachrome tautomerase antibodies...
Designing a Western blot for L-dopachrome tautomerase? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DCT Western Blot GuideDCT Infographic by Boster Bio
All DCT Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02175-2
100 μg/vial
Cat # A02175-2
100 μg/vial
Human, Mouse
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A11334-1
100 μg/vial
Cat # A11334-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01830-3
100 μg/vial
Cat # A01830-3
100 μg/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M12563
100 μl/vial
Cat # M12563
100 μl/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M11728
100 μl/vial
Cat # M11728
100 μl/vial
Mouse
ELISA
$750
Cat # EK2007
96 wells/kit, with removable strips.
Cat # EK2007
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA
$480
Cat # EKC1425
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1425
1 kit, containing one 96-well plate and all necessary reagents
DCT Overview
Facts about L-dopachrome tautomerase.
L-dopachrome tautomerase (DCT)
Catalyzes the conversion of L-dopachrome into 5,6- dihydroxyindole-2-carboxylic acid (DHICA) (PubMed:8306979). Involved in regulating eumelanin and phaeomelanin levels.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | DCT |
| Uniprot: | P40126 |
| Entrez: | 1638 |
Family
| Belongs to: |
|---|
| tyrosinase family |
Alternative Names
dopachrome delta-isomerase; dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2); DT; EC 5.3.3.12; L-dopachrome tautomerase; TRP2; TRP-2; Tyrosinase-related protein 2; TYRP2; TYRP2L-dopachrome Delta-isomerase
Molecular Weight
Mass (kDA):
59.145 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 13q32.1 |
| Sequence: | 13; NC_000013.11 (94436811..94549406, complement) |
Subcellular Localizations
Melanosome membrane; Single-pass type I membrane protein. Melanosome. Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38.
Diseases
- Intraocular Pressure Disorder
- Glaucoma
- Corneal Diseases
- Malignant Neoplasms
- Neoplasms
- Porphyria Cutanea Tarda
- Melanoma
- Hypertensive Disease
- Glaucoma, Open-angle
- Ocular Hypertension
- Crest Syndrome
- Mastitis, Bovine
Pathways
- Transport
- Pigmentation
- Localization
- Excretion
- Secretion
- Lactation
- Pathogenesis
- Melanocyte Differentiation
- Cell Proliferation
- Segmentation
- Glomerular Filtration
- Ion Transport
- Aging
PTMs
- Phosphorylation
- Carboxylation
- Cleavage
- Glycosylation
- Oxidation
- Sumoylation
- Deamination
- Decarboxylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DCT
bosterbio.com/bosterbio-gene-info-cards/DCT
References
PMID: 8148378 by Yokoyama K., et al. Molecular cloning and functional analysis of a cDNA coding for human DOPAchrome tautomerase/tyrosinase-related protein-2.
PMID: 8206391 by Cassady J.L., et al. Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA.