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May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting.
|class I-like SAM-binding methyltransferase superfamily|
|Sequence:||2; NC_000002.12 (25227874..25342590, complement)|
Highly expressed in fetal tissues, skeletal muscle, heart, peripheral blood mononuclear cells, kidney, and at lower levels in placenta, brain, liver, colon, spleen, small intestine and lung.
Nucleus. Cytoplasm. Accumulates in the major satellite repeats at pericentric heterochromatin.