DPYSL2 Antibodies

AND DPYSL2 ELISA kits, DPYSL2 Proteins

Many biological assays use antibodies to detect DPYSL2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DPYSL2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DPYSL2 antibodies...

We validate the specificity of these antibodies to DPYSL2 by testing them on tissues known to express DPYSL2 positively and negatively. Browse below to find the DPYSL2 antibody that suites your experiment. We have 10 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DPYSL2 Infographic by Boster Bio

All DPYSL2 Products

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Specificity

Applications

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Anti-CRMP-2 DPYSL2 Antibody

Immunofluorescence analysis of HeLa cells, using DRP-2 Antibody

Western Blot analysis of mouse brain cells using CRMP-2 Polyclonal Antibody

Western blot analysis of lysates from A549 cells, treated with EGF 200ng/ml 30

Human, Mouse, Rat

ELISA, IF, IHC, WB

$399
Cat # A02860-1
100μl

Anti-CRMP2 Rabbit Monoclonal Antibody

7 Q&As

Western blot analysis of CRMP2 expression in (1) U87-MG cell lysate; (2) NIH/3T3 cell lysate

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M02860
100 μl

CRMP2 Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HT-29 cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1144
1 kit, containing one 96-well plate and all necessary reagents

CRMP2 (Phospho-Thr514) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from NIH-3T3 cells treated with PMA 125ng/ml 30

Human, Mouse, Rat

ELISA

$540
Cat # EKC2333
1 kit, containing two 96-well plates and all necessary reagents

CRMP2 (Phospho-Thr509) Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HT29 cells treated with heat shock

Human, Mouse, Rat

ELISA

$540
Cat # EKC2611
1 kit, containing two 96-well plates and all necessary reagents

Anti-Phospho-CRMP-2 (S522) DPYSL2 Antibody

Western Blot analysis of Hela cells using Phospho-CRMP-2 (S522) Polyclonal Antibody diluted at 1:2000

Human, Mouse, Rat

ELISA, WB

$380
Cat # A02860S522
100ul

Anti-Phospho-CRMP-2 (T509) DPYSL2 Antibody

Western Blot analysis of various cells using primary antibody diluted at 1:1000 (4°C overnight)

Western Blot analysis of JK cells using Phospho-CRMP-2 (T509) Polyclonal Antibody

Western blot analysis of lysates from HT29 cells treated with heat shock, using CRMP-2 (Phospho-Thr509) Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A02860T509
100ul

Anti-Phospho-CRMP-2 (T514) DPYSL2 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A02860T514
100ul

Anti-CRMP2/DPYSL2 Antibody Picoband®

Western blot analysis of CRMP2/DPYSL2 using anti-CRMP2/DPYSL2 antibody (A02860-4)

IF analysis of CRMP2/DPYSL2 using anti-CRMP2/DPYSL2 antibody (A02860-4)

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # A02860-4
100 μg/vial

Anti-Phospho-CRMP2 (T514) Rabbit Monoclonal Antibody

All lanes use the Antibody at 1:6K dilution for 1 hour at room temperature

Human, Mouse, Rat

$370
Cat # M02860T514
100 µl/vial

DPYSL2 Overview

Facts about Dihydropyrimidinase-related protein 2.

DPYSL2 3D structure. Source: alphafold

Dihydropyrimidinase-related protein 2 (DPYSL2)

Plays a role in cerebral growth and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.

May play a role in endocytosis. .

Gene Information

Human
Gene Name:	DPYSL2
Uniprot:	Q16555
Entrez:	1808

Family

Belongs to:

metallo-dependent hydrolases superfamily

Alternative Names

Collapsin response mediator protein 2; CRMP-2; CRMP2N2A3; DHPRP2; dihydropyrimidinase-like 2 long form; dihydropyrimidinase-like 2; dihydropyrimidinase-related protein 2; DRP2collapsin response mediator protein hCRMP-2; DRP-2ULIP-2; ULIP2; Unc-33-like phosphoprotein 2

Molecular Weight

Mass (kDA):
62.294 kDA

Genomic Context


Human

Location:	8p21.2
Sequence:	8; NC_000008.11 (26514031..26658175)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Membrane. Tightly but non-covalently associated with membranes.

Diseases

Schizophrenia
Nervousness
Alzheimer's Disease
Bipolar Disorder
Mental Disorders
Brain Ischemia
Endoplasmic Reticulum Stress
Malignant Neoplasms
Neoplasms
Ischemia
Depressive Disorder
Infarction

Neurodegenerative Disorders
Cerebrovascular Accident
Ischemic Stroke
Nervous System Disorder
Virus Diseases
Autistic Disorder
Schizoaffective Disorder

Interacting Proteins

CRMP1
DPYSL5
GORASP2

Pathways

Translation
Transport
Vesicle Transport
Developmental Process
Proteolysis
Dna Methylation
Neural Rod Formation
Glycosylation
Cell Fate Determination
Neurogenesis
Myelination
Stem Cell Fate Determination
Methylation

Protein Glycosylation
Regeneration
Flight
Transmission Of Nerve Impulse
Social Behavior
Cognition
Pathogenesis

PTMs

Phosphorylation
Methylation

Glycosylation
Cleavage

Research Areas

Neuroscience
Phospho-Specific

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DPYSL2

References

PMID: 7637782 by Goshima Y., et al. Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33.

PMID: 8973361 by Hamajima N., et al. A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.