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Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase (PubMed:7512953, PubMed:7643093, PubMed:16423344, PubMed:27659709, PubMed:29051383). Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 from the retinal ganglion cells (By similarity).
|G-protein coupled receptor 1 family|
|Sequence:||11; NC_000011.10 (637269..640706)|
Highly expressed in retina. Detected at much lower levels in brain, in amygdala, thalamus, hypothalamus, cerebellum and pituitary.
Cell membrane; Multi-pass membrane protein.