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- Table of Contents
Desmoglein-2 Antibodies
AND DSG2 ELISA kits, Desmoglein-2 Proteins
Many biological assays use antibodies to detect Desmoglein-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Desmoglein-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Desmoglein-2 antibodies...
Designing a Western blot for Desmoglein-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DSG2 Western Blot GuideDSG2 Infographic by Boster Bio
All DSG2 Products
Product
Figures
Specificity
Applications
Price
Anti-Desmoglein 2/DSG2 Antibody Picoband®
3 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PA1559
100 μg/vial
Cat # PA1559
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02035
100 μg/vial
Cat # A02035
100 μg/vial
Human
IHC, WB
$370
Cat # M02035-2
100 μg/vial
Cat # M02035-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M02035
100 μl
Cat # M02035
100 μl
DSG2 Overview
Facts about Desmoglein-2.
Desmoglein-2 (DSG2)
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | DSG2 |
| Uniprot: | Q14126 |
| Entrez: | 1829 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
ARVC10; ARVD10; Cadherin family member 5; CDHF5; CDHF5MGC117034; CMD1BB; desmoglein 2; Desmoglein2; Desmoglein-2; DSG2; HDGC; MGC117036; MGC117037
Molecular Weight
Mass (kDA):
122.294 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18q12.1 |
| Sequence: | 18; NC_000018.10 (31498177..31549008) |
Tissue Specificity
All of the tissues tested and carcinomas.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Diseases
- Tissue Adhesions
- Arrhythmogenic Right Ventricular Dysplasia
- Neoplasms
- Cardiomyopathies
- Malignant Neoplasms
- Carcinoma
- Cardiac Arrhythmia
- Dental Plaque
- Pemphigus Foliaceus
- Neoplasm Metastasis
- Malignant Squamous Cell Neoplasm
- Sudden Death
Pathways
- Cell Adhesion
- Cell-cell Adhesion
- Pathogenesis
- Localization
- Desmosome Assembly
- Cell Proliferation
- Cell Migration
- Cell Death
- Keratinization
- Transport
- Keratinocyte Differentiation
- Inflammatory Response
- Epithelial Cell-cell Adhesion
PTMs
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DSG2
bosterbio.com/bosterbio-gene-info-cards/DSG2
References
PMID: 8143788 by Schaefer S., et al. Identification of the ubiquitous human desmoglein, Dsg2, and the expression catalogue of the desmoglein subfamily of desmosomal cadherins.
PMID: 1935985 by Koch P.J., et al. Complete amino acid sequence of the epidermal desmoglein precursor polypeptide and identification of a second type of desmoglein gene.