DUSP3 Antibodies

AND DUSP3 ELISA kits, DUSP3 Proteins

Many biological assays use antibodies to detect DUSP3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DUSP3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DUSP3 antibodies...

We validate the specificity of these antibodies to DUSP3 by testing them on tissues known to express DUSP3 positively and negatively. Browse below to find the DUSP3 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DUSP3 Infographic by Boster Bio

All DUSP3 Products

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Applications

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Anti-DUSP3 Antibody Picoband®

4 Q&As

Western blot analysis of DUSP3 using anti-DUSP3 antibody (PA1762)

Human, Mouse, Rat

$370
Cat # PA1762
100 μg/vial

Anti-DUSP3 Picoband® Antibody

Western blot analysis of DUSP3 using anti-DUSP3 antibody (A06135)

Flow Cytometry analysis of THP-1 cells using anti-DUSP3 antibody (A06135)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A06135
100 μg/vial

Anti-VHR DUSP3 Antibody

Western Blot analysis of HepG2 cells using VHR Polyclonal Antibody

Western blot analysis of lysate from HepG2 cells, using DUSP3 Antibody

Immunohistochemical analysis of paraffin-embedded mouse-kidney, antibody was diluted at 1:100

Human, Mouse, Rat

ELISA, IF, IHC, WB

$380
Cat # A06135-1
100ul

DUSP3 (NM_004090) Human Recombinant Protein

Coomassie blue staining of purified DUSP3 protein

$1249
Cat # PROTP51452
20 µg

Anti-DUSP3 Mouse Monoclonal Antibody [Clone ID: OTI2B12]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DUSP3 (Right lane) cDNA for 48 hrs and lysed

Human, Mouse, Rat

$523
Cat # M06135
100 µl

DUSP3 (NM_004090) Human Over-expression Lysate

Human

$628
Cat # LS001845
20 µg, 100 µg

DUSP3 Overview

Facts about Dual specificity protein phosphatase 3.

DUSP3 3D structure. Source: alphafold

Dual specificity protein phosphatase 3 (DUSP3)

Shows action both for tyrosine-protein phosphate and serine-protein phosphate, but shows a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2.

Gene Information

Human
Gene Name:	DUSP3
Uniprot:	P51452
Entrez:	1845

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

dual specificity phosphatase 3; dual specificity protein phosphatase 3; Dual specificity protein phosphatase VHR; DUSP3; EC 3.1.3.16; EC 3.1.3.48; Vaccinia H1-related phosphatase; vaccinia virus phosphatase VH1-related; VHR; VHRserine/threonine specific protein phosphatase

Molecular Weight

Mass (kDA):
20.478 kDA

Genomic Context


Human

Location:	17q21.31
Sequence:	17; NC_000017.11 (43766125..43778977, complement)

Subcellular Localizations

Nucleus.

Diseases

Vaccinia
Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Dementia
Carcinoma
Posttransfusion Purpura
Mammary Neoplasms
Malignant Squamous Cell Neoplasm
Heredopathia Ophthalmootoencephalica
Neurodegenerative Disorders
Uterine Cervical Neoplasm

Malignant Tumor Of Cervix
Malignant Neoplasm Of Lung
Parkinson Disease
Patient Dependence On
Yersinia Infections
Cervical Intraepithelial Neoplasia
Pituitary Diseases

Pathways

Cell Cycle
Rna Interference
Localization
Senescence
Dna Replication
Cell Growth
Mrna Processing
Cell Activation
Cell Proliferation
T Cell Activation
Aging

Cell Cycle Arrest
Cell Division
Sperm Motility
Cell Cycle Process
Pathogenesis

PTMs

Phosphorylation
Dephosphorylation

Reduction
Cleavage

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DUSP3

References

PMID: 1281549 by Ishibashi T., et al. Expression cloning of a human dual-specificity phosphatase.

PMID: 10224087 by Todd J.L., et al. Extracellular regulated kinases (ERK) 1 and ERK2 are authentic substrates for the dual-specificity protein-tyrosine phosphatase VHR. A novel role in down-regulating the ERK pathway.