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- Table of Contents
Protein Dok-7 Antibodies
AND Dok7 ELISA kits, Protein Dok-7 Proteins
Many biological assays use antibodies to detect Protein Dok-7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein Dok-7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein Dok-7 antibodies...
Designing a Western blot for Protein Dok-7? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DOK7 Western Blot GuideDesigning an IHC experiment for Protein Dok-7? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the DOK7 IHC GuideDok7 Infographic by Boster Bio
All Dok7 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # A05165-1
100 μg/vial
Cat # A05165-1
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05166-1
100 µg/vial
Cat # A05166-1
100 µg/vial
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A05173-2
100 μg/vial
Cat # A05173-2
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05171-3
100 µg/vial
Cat # A05171-3
100 µg/vial
Human, Mouse
ELISA
$480
Cat # EKC1841
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1841
1 kit, containing one 96-well plate and all necessary reagents
Dok7 Overview
Facts about Protein Dok-7.
Protein Dok-7 (Dok7)
Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes.
Induces autophosphorylation of MUSK. .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Dok7 |
| Uniprot: | Q18PE0 |
| Entrez: | 231134 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
C4orf25; C4orf25chromosome 4 open reading frame 25; CMS1B; docking protein 7; DOK7; Dok-7; Downstream of tyrosine kinase 7; FLJ33718; FLJ39137; FLJ90556; protein Dok-7
Molecular Weight
Mass (kDA):
53.177 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 5|5 B2 |
| Sequence: | 5; |
Diseases
- Myasthenic Syndromes, Congenital
- Weakness
- Myasthenias
- Muscle Weakness
- Myasthenia Gravis
- Autoimmune Reaction
- Autoimmune Diseases
- Blepharoptosis
- Muscular Dystrophies, Limb-girdle
- Myopathy
- Malignant Neoplasms
Pathways
- Localization
- Pathogenesis
- Muscle Contraction
- Dna Hypermethylation
- Aging
- Dna Methylation
- Synaptic Transmission
- Muscle Atrophy
- Nuclear Export
- Methylation
- Regeneration
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dok7
bosterbio.com/bosterbio-gene-info-cards/Dok7
References
PMID: 16794080 by Okada K., et al. The muscle protein Dok-7 is essential for neuromuscular synaptogenesis.
PMID: 20603078 by Bergamin E., et al. The cytoplasmic adaptor protein Dok7 activates the receptor tyrosine kinase MuSK via dimerization.
1 Publications of Boster Protein Dok-7 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.biopha.2018.06.156, Repression of Dok7 expression mediated by DNMT1 promotes glioma cells proliferat...
*More publications can be found for each product on its corresponding product page