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- Table of Contents
Facts about Elongator complex protein 3.
May also have a methyltransferase activity. Involved in cell migration.
Human | |
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Gene Name: | ELP3 |
Uniprot: | Q9H9T3 |
Entrez: | 55140 |
Belongs to: |
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ELP3 family |
EC 2.3.1.48; elongation protein 3 homolog (S. cerevisiae); elongator complex protein 3; hELP3; KAT9FLJ10422
Mass (kDA):
62.259 kDA
Human | |
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Location: | 8p21.1 |
Sequence: | 8; NC_000008.11 (28090232..28191153) |
Expressed in the cerebellum and spinal motor neurons.
Cytoplasm. Nucleus.; [Isoform 1]: Nucleus.; [Isoform 2]: Cytoplasm. Nucleus.
You may have questions about the optimization of your experiments or flow procedures. Fortunately, Boster Bio has optimized many experiments for you. This article discusses optimization tips and guides. In addition, we discuss some of the different options available for targeting the 3'-UTR. Read on to learn more. Boster Bio: Best Uses Of The ELP3 Marker
There are several options when optimizing your flow cytometry experiments, including the ELP3 marker. The following tips will help you optimize your experiments. In addition to a detailed overview of the procedure, Boster Bio offers troubleshooting guides and gene infographics for each marker. You can quickly find the gene you're looking for and then follow the specific guidelines in the guide to optimize the experiment.
If you're looking for a quick and convenient way to detect the presence of ELP3 in your cells, a cell-based ELISA kit is the perfect choice. With a single, easy-to-follow protocol, cell-based ELISA kits can detect both non-phosphorylated and phosphorylated targets. This enables you to compare the levels of ELP3 in various cell lines.
Cellular ELISA kits for the ELP3 marker must be designed to measure acetylation of histones in cells. However, this is not a straightforward task because histone acetylation is a complex process involving multiple factors. For example, HAT expression, histone deacetylase activity, cell cycle effects, and the rates of histone synthesis and degradation all confound the results. Additionally, cellular ELISA kits for the ELP3 marker are limited by their lower precision and smaller dynamic range.
Several studies have found that the ELP3 marker in GC cells is associated with tumor growth. The protein has several functions in cancer cell biology. It is an essential regulator of the autophagy pathway. It also acts as a tumor suppressor by inhibiting the expression of genes such as CDC42 and PIK3CA. Boster Bio has published several papers demonstrating the use of ELP3 in cancer research.
PMID: 11714725 by Hawkes N.A., et al. Purification and characterization of the human elongator complex.
PMID: 11818576 by Kim J.H., et al. Human Elongator facilitates RNA polymerase II transcription through chromatin.