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- Table of Contents
ERBB2 Antibodies
AND ERBB2 ELISA kits, ERBB2 Proteins
Many biological assays use antibodies to detect ERBB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ERBB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ERBB2 antibodies...
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ERBB2 Infographic by Boster Bio
All ERBB2 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0756
96 wells/kit, with removable strips.
Cat # EK0756
96 wells/kit, with removable strips.
Anti-ErbB 2/ERBB2 Antibody Picoband®
5 Citations 16 Q&As
Human
IHC, WB
$370
Cat # A00010-2
100 μg/vial
Cat # A00010-2
100 μg/vial
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00010-1
100 μl
Cat # M00010-1
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1270
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1270
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2426
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2426
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2427
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2427
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2428
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2428
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2551
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2551
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
IHC
$482
Cat # A00010Y1221Y1222
100ul
Cat # A00010Y1221Y1222
100ul
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$380
Cat # A00010Y1221Y1222-1
100ul
Cat # A00010Y1221Y1222-1
100ul
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M00010-4
100 µl
Cat # M00010-4
100 µl
Anti-HER2/ERBB2 Antibody Picoband®
1 Citations
Human, Mouse
ELISA, IHC, WB
$370
Cat # A00010-4
100 μg/vial
Cat # A00010-4
100 μg/vial
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00010-5
100 μg/vial
Cat # A00010-5
100 μg/vial
Human
WB
$370
Cat # M00010Y1221Y1222
100 µl/vial
Cat # M00010Y1221Y1222
100 µl/vial
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-5
100 μg
Cat # M00010-5
100 μg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-6
100 μg
Cat # M00010-6
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-7
100 μg
Cat # M00010-7
100 μg
Human, Mouse, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-8
100 μg
Cat # M00010-8
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-10
100 μg
Cat # M00010-10
100 μg
Cynomolgus monkey, Human, Mouse, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-11
100 μg
Cat # M00010-11
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-12
100 μg
Cat # M00010-12
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-13
100 μg
Cat # M00010-13
100 μg
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-14
100 μg
Cat # M00010-14
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-15
100 μg
Cat # M00010-15
100 μg
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-16
100 μg
Cat # M00010-16
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-17
100 μg
Cat # M00010-17
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-18
100 μg
Cat # M00010-18
100 μg
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-19
100 μg
Cat # M00010-19
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-20
100 μg
Cat # M00010-20
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00010-9
100 μg
Cat # M00010-9
100 μg
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00010-21
20μL, 40μL, 100μL, 200μL
Cat # M00010-21
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # P00010-2
100 μl/vial
Cat # P00010-2
100 μl/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # P00010-3
100 μl/vial
Cat # P00010-3
100 μl/vial
ERBB2 Overview
Facts about Receptor tyrosine-protein kinase erbB-2.
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
Protein tyrosine kinase that's part of many cell surface receptor complexes, but that apparently wants a coreceptor for ligand binding. Essential element of a neuregulin-receptor complex, although neuregulins don't interact with it alone.
GP30 is a potential ligand for this receptor. Regulates outgrowth and insertion of peripheral microtubules (MTs).
Gene Information
| Human | |
|---|---|
| Gene Name: | ERBB2 |
| Uniprot: | P04626 |
| Entrez: | 2064 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
CD340 antigen; CD340; c-erb B2/neu protein; EC 2.7.10; EGFR2; ErbB2; HER2; HER-2; HER2EC 2.7.10.1; herstatin; Metastatic lymph node gene 19 protein; MLN 19; MLN19; Neu Oncogene; NEUHER-2/neu; neuroblastoma/glioblastoma derived oncogene homolog; NGL; NGLTKR1; p185erbB2; Proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog); v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomade
Molecular Weight
Mass (kDA):
137.91 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q12 |
| Sequence: | 17; NC_000017.11 (39688084..39728662) |
Tissue Specificity
Expressed in a variety of tumor tissues including primary breast tumors and tumors from small bowel, esophagus, kidney and mouth.
Subcellular Localizations
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Early endosome. Cytoplasm, perinuclear region. Nucleus. Translocation to the nucleus requires endocytosis, probably endosomal sorting and is mediated by importin beta-1/KPNB1. Also detected in VPS35-positive endosome-to-TGN retrograde vesicles (PubMed:31138794).; [Isoform 2]: Cytoplasm. Nucleus.; [Isoform 3]: Cytoplasm. Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
- Carcinoma
- Neoplasm Metastasis
- Cell Transformation, Neoplastic
- Adenocarcinoma
- Malignant Paraganglionic Neoplasm
- Ductal Breast Carcinoma
- Cell Invasion
- Neoplasm Invasiveness
Pathways
- Cell Proliferation
- Cell Growth
- Cell Cycle
- Localization
- Angiogenesis
- Pathogenesis
- Cell Death
- Cell Migration
- Secretion
- Oncogenesis
- Cell Motility
- Drug Resistance
- Endocytosis
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Ubiquitination
- Dephosphorylation
- Biotinylation
- Acetylation
- Glycosylation
- Reduction
- Demethylation
Research Areas
- Breast Cancer
- Cancer
- Cellular Markers
- Core ESC-Like Genes
- Phospho-Specific
- Protein Kinase
- Stem Cell Markers
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ERBB2
bosterbio.com/bosterbio-gene-info-cards/ERBB2
References
PMID: 3003577 by Yamamoto T., et al. Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor.
PMID: 2999974 by Coussens L., et al. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene.
6 Publications of Boster ERBB2 Antibodies & ELISA Kits
- PubMed ID: 10.3390/ijms14048422, MiR199b Suppresses Expression of Hypoxia-Inducible Factor 1α (HIF-1α) in Prost...
- PubMed ID: 10.1038/aps.2014.26, Lapatinib-incorporated lipoprotein-like nanoparticles: preparation and a propose...
- PubMed ID: 10.1016/j.ijpharm.2013.12.016, Incorporation of lapatinib into core–shell nanoparticles improves both the sol...
- PubMed ID: 24902791, Lapatinib-incorporated lipoprotein-like nanoparticles: preparation and a propose...
- PubMed ID: 28667103, Tong ZJ, Shi NY, Zhang ZJ, Yuan XD, Hong XM. Biosci Rep. 2017 Aug 2;37(4). pii: ...
- PubMed ID: 21392403, Tao L, Suhua C, Juanjuan C, Zongzhi Y, Juan X, Dandan Z. Virol J. 2011 Mar 11;8:...
*More publications can be found for each product on its corresponding product page