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- Table of Contents
ETF1 Antibodies
AND ETF1 ELISA kits, ETF1 Proteins
Many biological assays use antibodies to detect ETF1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ETF1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ETF1 antibodies...
Designing a Western blot for ETF1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ETF1 Western Blot GuideETF1 Infographic by Boster Bio
All ETF1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M04157
100 μg/vial
Cat # M04157
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M04157-1
100 μg/vial
Cat # M04157-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A04164-2
100 μg/vial
Cat # A04164-2
100 μg/vial
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A04161-1
100 μg/vial
Cat # A04161-1
100 μg/vial
ETF1 Overview
Facts about Eukaryotic peptide chain release factor subunit 1.
Eukaryotic peptide chain release factor subunit 1 (ETF1)
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Part of the transient SURF complicated which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | ETF1 |
| Uniprot: | P62495 |
| Entrez: | 2107 |
Family
| Belongs to: |
|---|
| eukaryotic release factor 1 family |
Alternative Names
D5S1995; ERF1eRF1; eukaryotic peptide chain release factor subunit 1; Eukaryotic release factor 1; eukaryotic translation termination factor 1; polypeptide chain release factor 1; Protein Cl1; RF1ERF; sup45 (yeast omnipotent suppressor 45) homolog-like 1; SUP45L1; TB3-1MGC111066
Molecular Weight
Mass (kDA):
49.031 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q31.2 |
| Sequence: | 5; NC_000005.10 (138506093..138543236, complement) |
Subcellular Localizations
Cytoplasm.
Diseases
- Neoplasms
- Malignant Neoplasms
- Myeloid Leukemia
- Hereditary Diseases
- Malignant Paraganglionic Neoplasm
- Leukemia
- Sclerosis
- Myeloid Neoplasm
- Primary Lateral Sclerosis
- Stenosis
- Neurodegenerative Disorders
- Malignant Neoplasm Of Breast
- Infectious Mononucleosis
Interacting Proteins
- GSPT1
- GSPT2
- KEAP1
Pathways
- Translation
- Translational Termination
- Cell Cycle
- Translational Readthrough
- Methylation
- Dna Replication
- Pathogenesis
- Rna Interference
- Transport
- Cvt Pathway
- Selenocysteine Incorporation
- Proteolysis
- Virulence
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ETF1
bosterbio.com/bosterbio-gene-info-cards/ETF1
References
PMID: 1537561 by Grenett H.E., et al. Identification of a human cDNA with high homology to yeast omnipotent suppressor 45.
PMID: 7990965 by Frolova L., et al. A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor.