ETF1 Antibodies

Eukaryotic peptide chain release factor subunit 1 (ETF1)

Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Part of the transient SURF complicated which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

.

Gene Information

Human
Gene Name:	ETF1
Uniprot:	P62495
Entrez:	2107

Family

Belongs to:
eukaryotic release factor 1 family

Alternative Names

D5S1995; ERF1eRF1; eukaryotic peptide chain release factor subunit 1; Eukaryotic release factor 1; eukaryotic translation termination factor 1; polypeptide chain release factor 1; Protein Cl1; RF1ERF; sup45 (yeast omnipotent suppressor 45) homolog-like 1; SUP45L1; TB3-1MGC111066

Molecular Weight

Mass (kDA):
49.031 kDA

Genomic Context

Human
Location:	5q31.2
Sequence:	5; NC_000005.10 (138506093..138543236, complement)

Subcellular Localizations

Cytoplasm.

Diseases

• Neoplasms
• Malignant Neoplasms
• Myeloid Leukemia
• Hereditary Diseases
• Malignant Paraganglionic Neoplasm
• Leukemia
• Sclerosis
• Myeloid Neoplasm
• Primary Lateral Sclerosis
• Stenosis
• Neurodegenerative Disorders
• Malignant Neoplasm Of Breast
• Infectious Mononucleosis

• Malignant Tumor Of Colon
• Muscular Dystrophy, Duchenne
• Amyotrophic Lateral Sclerosis
• Leukemia, Myelocytic, Acute
• Fracture
• Hemolysis (disorder)
• Patient Dependence On

Interacting Proteins

• GSPT1
• GSPT2
• KEAP1

Pathways

• Translation
• Translational Termination
• Cell Cycle
• Translational Readthrough
• Methylation
• Dna Replication
• Pathogenesis
• Rna Interference
• Transport
• Cvt Pathway
• Selenocysteine Incorporation
• Proteolysis
• Virulence

• Cell Cycle Arrest
• Cytoskeleton Organization
• Rna Surveillance
• Macroautophagy
• Bone Development
• Regulation Of Mrna Stability
• Cell Proliferation

PTMs

• Phosphorylation
• Cleavage

• Biotinylation
• Methylation

• Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ETF1

Boster Bio - Best Uses Of The ETF1 Marker

Boster Bio provides high affinity research primary antibodies to scientists who are looking for the best way to measure protein activity in the body. Researchers and clinicians can quickly and easily find the right product with their PICOKINE(tm), Bioz Citation Counters and Bioz Citation Badges. These markers increase researcher confidence and trust.

Boster Bio's high affinity primary antibodies are for research purposes.

Boster Bio high-affinity products can be used to test your hypothesis or analyze ELISA results. They are available for a variety applications including IHC, WB and FC as well as ELISA and ELISA. They are available in both human and mouse formats and include a free secondary antibody.

To make a high affinity research antibody, it must be possible to access the epitope in tissue. This is known as the affinity constant. It is a measurement that measures how tightly an antibody can bind to antigen. To make sure that the antibody is highly specific, the ETF1 marker has been used as a guide to select a high-affinity antibody.

Bioz Citation Counters

The ETF1 marker is a protein that is expressed by several types of cells, including neurons and glia. It is present in all body tissues and is a key component of many biological process. It can be expressed within cells by the ribosomes. Boster Bio provides antibodies to this protein for various purposes, including immunohistochemistry, ELISA, and Western Blotting.

Boster Biologicals produces research antibodies, ELISA and WB/IHC-compatible antibodies. Their product range covers many areas including immunology and cancer, neurosciences and development. It is the sole company that designs and produces antibodies for this protein. Boster Bio has a wealth of experience in antibody designing and has developed a product line to help clients with their research.