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- Table of Contents
Ezrin Antibodies
AND EZR ELISA kits, Ezrin Proteins
Many biological assays use antibodies to detect Ezrin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ezrin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ezrin antibodies...
Designing a Western blot for Ezrin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the EZR Western Blot GuideEZR Infographic by Boster Bio
All EZR Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01750-2
100 μg/vial
Cat # A01750-2
100 μg/vial
Human, Mouse, Rat
ELISA, IHC, WB
$370
Cat # A02427-1
100 μg/vial
Cat # A02427-1
100 μg/vial
Anti-ALIX Rabbit Monoclonal Antibody
3 Citations
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # M01751
100 μl
Cat # M01751
100 μl
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00279-2
100 μg/vial
Cat # A00279-2
100 μg/vial
Human, Mouse, Rat
IF, WB
$523
Cat # M01750-1
100 µl
Cat # M01750-1
100 µl
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00766T558
100ul
Cat # A00766T558
100ul
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01750-2
20μL, 40μL, 100μL, 200μL
Cat # M01750-2
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA
$540
Cat # EKC2548
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2548
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2405
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2405
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1608
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1608
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2307
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2307
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1384
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1384
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2460
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2460
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1363
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1363
1 kit, containing one 96-well plate and all necessary reagents
Human
WB
$482
Cat # A01750T567T564T558
100ul
Cat # A01750T567T564T558
100ul
EZR Overview
Facts about Ezrin.
Ezrin (EZR)
Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole.
Along with PLEKHG6, required for normal macropinocytosis. .
Gene Information
| Human | |
|---|---|
| Gene Name: | EZR |
| Uniprot: | P15311 |
| Entrez: | 7430 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CVIL; CVL; Cytovillin 2; Cytovillin; DKFZp762H157; EZR; Ezrin; FLJ26216; p81; VIL2; VIL2MGC1584; villin 2 (ezrin); Villin 2; villin-2
Molecular Weight
Mass (kDA):
69.413 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6q25.3 |
| Sequence: | 6; NC_000006.12 (158765744..158819368, complement) |
Tissue Specificity
Expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. Weakly expressed in brain stem and diencephalon. Stronger expression was detected in gray matter of frontal lobe compared to white matter (at protein level). Component of the microvilli of intestinal epithelial cells. Preferentially expressed in astrocytes of hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Not detected in neurons in most tissues studied.
Subcellular Localizations
Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell projection, microvillus. Localization to the apical membrane of parietal cells depends on the interaction with MPP5. Localizes to cell extensions and peripheral processes of astrocytes (By similarity). Microvillar peripheral membrane protein (cytoplasmic side).
Diseases
- Neoplasms
- Cell Invasion
- Neoplasm Metastasis
- Neoplasm Invasiveness
- Tissue Adhesions
- Osteoblastoma
- Tumor Progression
- Malignant Neoplasm Of Breast
- Bone Neoplasms
- Carcinoma
- Endoplasmic Reticulum Stress
- Giant Cell Tumors
- Osteosarcoma
Interacting Proteins
- CAPN1
- Dcc
- FES
- MDM2
- MISP
- RDX
- SCYL3
- SLC12A2
- SLC9A3R1
Pathways
- Cell Adhesion
- Regeneration
- Actin Cytoskeleton Organization
- Cytoskeleton Organization
- Response To Stress
- Cell Migration
- Cell Proliferation
- Neuron Development
PTMs
- Acetylation
Research Areas
- Cancer
- Cell Cycle and Replication
- Phospho-Specific
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EZR
bosterbio.com/bosterbio-gene-info-cards/EZR
References
PMID: 2591371 by Gould K.L., et al. cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1.
PMID: 2674140 by Turunen O., et al. Cytovillin, a microvillar Mr 75,000 protein. cDNA sequence, prokaryotic expression, and chromosomal localization.
1 Publications of Boster Ezrin Antibodies & ELISA Kits
- PubMed ID: 32400849, Cao G,Meng X, Han X,Li J.Exosomes derived from circRNA Rtn4-modified BMSCs atten...
*More publications can be found for each product on its corresponding product page