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- Table of Contents
F2R Antibodies
AND F2R ELISA kits, F2R Proteins
Many biological assays use antibodies to detect F2R, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with F2R in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop F2R antibodies...
Designing a Western blot for F2R? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the F2R Western Blot GuideF2R Infographic by Boster Bio
All F2R Products
Product
Figures
Specificity
Applications
Price
Anti-PAR2 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01081
100 μl/vial
Cat # M01081
100 μl/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A03352-1
100 μg/vial
Cat # A03352-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03352-2
100 μg/vial
Cat # A03352-2
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01081-3
100 μg
Cat # M01081-3
100 μg
Human, Mouse, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01081-2
100 μg
Cat # M01081-2
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01081-1
100 μg
Cat # M01081-1
100 μg
Human
$628
Cat # LS002149
20 µg, 100 µg
Cat # LS002149
20 µg, 100 µg
Human
$628
Cat # LS009002
20 µg, 100 µg
Cat # LS009002
20 µg, 100 µg
Human
$628
Cat # LS002151
20 µg, 100 µg
Cat # LS002151
20 µg, 100 µg
F2R Overview
Facts about Proteinase-activated receptor 1.
Proteinase-activated receptor 1 (F2R)
High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in cerebral growth.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | F2R |
| Uniprot: | P25116 |
| Entrez: | 2149 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 1 family |
Alternative Names
Cf2r; CF2RHTR; coagulation factor II (thrombin) receptor; Coagulation factor II receptor; F2R; HTR; PAR1; PAR1PAR-1protease-activated receptor 1; Protease-Activated Receptor 1; Thrombin receptor; ThrR; TRGPC; TRproteinase-activated receptor 1
Molecular Weight
Mass (kDA):
47.441 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q13.3 |
| Sequence: | 5; NC_000005.10 (76716126..76735770) |
Tissue Specificity
Platelets and vascular endothelial cells.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.
Diseases
- Malignant Neoplasms
- Neoplasms
- Neoplasm Metastasis
- Tumor Angiogenesis
- Inflammation
- Infarction
- Myocardial Infarction
- Tissue Adhesions
- Rabies (disorder)
- Stomach Neoplasms
- Carcinoma
- Globus Hystericus
- Premature Obstetric Labor
Interacting Proteins
- CAV1
- PROCR
Pathways
- Coagulation
- Angiogenesis
- Transport
- Blood Coagulation
- Immune Response
- Hemostasis
- Cell Adhesion
- Response To Wounding
- Cell Migration
- Response To Hypoxia
- Glycosylation
- Localization
- Defense Response
PTMs
- Phosphorylation
- Glycosylation
Research Areas
- Apoptosis
- GPCR
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/F2R
bosterbio.com/bosterbio-gene-info-cards/F2R
References
PMID: 1672265 by Vu T.-K.H., et al. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation.
PMID: 8955127 by Shapiro M.J., et al. Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonist-triggered versus tonic internalization and intracellular localization.
1 Publications of Boster F2R Antibodies & ELISA Kits
- PubMed ID: 27906434, D. QUANJUN, Z. QINGYU, Z. QILIANG, X. LIQUN, C. JINMEI, L. ZIQUAN, H. SHIKE Eur ...
*More publications can be found for each product on its corresponding product page