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- Table of Contents
FCGR1A Antibodies
AND FCGR1A ELISA kits, FCGR1A Proteins
Many biological assays use antibodies to detect FCGR1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FCGR1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FCGR1A antibodies...
Designing a Western blot for FCGR1A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the FCGR1A Western Blot GuideFCGR1A Infographic by Boster Bio
All FCGR1A Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A02428-3
100 μg/vial
Cat # A02428-3
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M02428-2
100 μg
Cat # M02428-2
100 μg
Human, Primate
Flow Cytometry, IP, IHC-P, IHC-F, ICC, WB
$299
Cat # M02428
0.1 mg
Cat # M02428
0.1 mg
FCGR1A Overview
Facts about High affinity immunoglobulin gamma Fc receptor I.
High affinity immunoglobulin gamma Fc receptor I (FCGR1A)
High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | FCGR1A |
| Uniprot: | P12314 |
| Entrez: | 2209 |
Family
| Belongs to: |
|---|
| immunoglobulin superfamily |
Alternative Names
CD64 antigen; CD64; CD64a; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc gamma RI; FCG1; Fc-gamma receptor I B2; Fc-gamma RI; Fc-gamma RIA; FcgammaRIa; FCGR1; FcgRI; FcgRIA; FCRI; FcRIA; FLJ18345; high affinity Ia, receptor for (CD64); high affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I
Molecular Weight
Mass (kDA):
42.632 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q21.2 |
| Sequence: | 1; NC_000001.11 (149782071..149792518) |
Tissue Specificity
Monocyte/macrophage specific.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Stabilized at the cell membrane through interaction with FCER1G.
Diseases
- Inflammation
- Autoimmune Diseases
- Autoimmune Reaction
- Allergy
- Arthritis
- Neoplasms
- Rheumatoid Arthritis
- Infective Disorder
- Immediate Hypersensitivity
- Atherosclerosis
- Acute Basophilic Leukemia
- Immune Complex Diseases
Interacting Proteins
- FCER1G
- IGHG1
Pathways
- Phagocytosis
- Immune Response
- Secretion
- Pathogenesis
- Cell Activation
- Type Iii Hypersensitivity
- Hypersensitivity
- Chemotaxis
- Cell Differentiation
- Innate Immune Response
- Antibody-dependent Cellular Cytotoxicity
- Monocyte Activation
- Cell Proliferation
PTMs
- Phosphorylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FCGR1A
bosterbio.com/bosterbio-gene-info-cards/FCGR1A
References
PMID: 2974947 by Allen J.M., et al. Nucleotide sequence of three cDNAs for the human high affinity Fc receptor (FcRI).
PMID: 2911749 by Allen J.M., et al. Isolation and expression of functional high-affinity Fc receptor complementary DNAs.