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- Table of Contents
FCGR3A Antibodies
AND FCGR3A ELISA kits, FCGR3A Proteins
Many biological assays use antibodies to detect FCGR3A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FCGR3A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FCGR3A antibodies...
Designing an IHC experiment for FCGR3A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the FCGR3A IHC GuideFCGR3A Infographic by Boster Bio
All FCGR3A Products
Product
Figures
Specificity
Applications
Price
Anti-CD16 Rabbit Monoclonal Antibody
4 Citations
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M01408-1
100 μl/vial
Cat # M01408-1
100 μl/vial
Anti-CD16/FCGR3A Antibody
2 Citations
Human
ELISA, Flow Cytometry, IF, IHC, ICC
$370
Cat # A01408-1
100 μg/vial
Cat # A01408-1
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01408-3
100 μg
Cat # M01408-3
100 μg
SDS-PAGE, Bioactivity
$282
Cat # PROTP08637-5
Starting from 10ug
Cat # PROTP08637-5
Starting from 10ug
SDS-PAGE, Bioactivity
$275
Cat # PROTP08637-4
Starting from 10ug
Cat # PROTP08637-4
Starting from 10ug
FCGR3A Overview
Facts about Low affinity immunoglobulin gamma Fc region receptor III-A.
Low affinity immunoglobulin gamma Fc region receptor III-A (FCGR3A)
Receptor for the Fc region of IgG.
Binds complexed or aggregated IgG and also monomeric IgG.Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. .
Gene Information
| Human | |
|---|---|
| Gene Name: | FCGR3A |
| Uniprot: | P08637 |
| Entrez: | 2214 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD16a antigen; CD16a; CD16FCRIIIA; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc gamma receptor III-A; Fc gamma RIIIA; FCG3; Fc-gamma receptor III-2 (CD 16); Fc-gamma receptor IIIb (CD16); Fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; FCGR3; FCGR3A; FCGRIII; FcgRIIIA; FcR-10; FCRIII; FcRIIIa; IGFR3FcgammaRIIIA; immunoglobulin G Fc receptor III; low affinity III, receptor for (CD16); low affinity immunoglobulin gamma Fc region receptor III-A; neutrophil-specific antigen NA
Molecular Weight
Mass (kDA):
29.089 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q23.3 |
| Sequence: | 1; NC_000001.11 (161541759..161550737, complement) |
Tissue Specificity
Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Secreted. Exists also as a soluble receptor.
Diseases
- Lymphoma
- Malignant Neoplasms
- Arthritis
- Rheumatoid Arthritis
- Neoplasms
- Lupus Erythematosus, Systemic
- Autoimmune Reaction
- Autoimmune Diseases
- Lymphoma, Non-hodgkin
- B-cell Lymphomas
- Lymphoma, Follicular
- Colorectal Cancer
- Colorectal Neoplasms
Pathways
- Antibody-dependent Cellular Cytotoxicity
- Pathogenesis
- Glycosylation
- Immune Response
- Complement-dependent Cytotoxicity
- Phagocytosis
- Macrophage Activation
- Fucosylation
- Cytokine Production
- Hypersensitivity
- Secretion
- Inflammatory Response
- Cell Proliferation
PTMs
- Glycosylation
- Citrullination
Research Areas
- Cell Biology
- Cellular Markers
- Cytokine Research
- Growth and Development
- Hematopoietic Stem Cell Markers
- Immunology
- Innate Immunity
- Neuronal Cell Markers
- Neuroscience
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FCGR3A
bosterbio.com/bosterbio-gene-info-cards/FCGR3A
References
PMID: 2526846 by Ravetch J.V., et al. Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions.
PMID: 16951347 by Rogers K.A., et al. IgG Fc receptor III homologues in nonhuman primate species: genetic characterization and ligand interactions.
3 Publications of Boster FCGR3A Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.lfs.2020.118582, Fingolimod suppressed the chronic unpredictable mild stress-induced depressive-l...
- PubMed ID: 10.1007/s11434-015-0961-2, IP-10 and fractalkine induce cytotoxic phenotype of murine NK cells
- PubMed ID: -, xiangrong chen,Yile Zeng,Fan Wang et al.ADAM17 Aggravates the Inflammatory ...
*More publications can be found for each product on its corresponding product page