Squalene synthase Antibodies

AND FDFT1 ELISA kits, Squalene synthase Proteins

Many biological assays use antibodies to detect Squalene synthase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Squalene synthase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Squalene synthase antibodies...

We validate the specificity of these antibodies to Squalene synthase by testing them on tissues known to express FDFT1 positively and negatively. Browse below to find the FDFT1 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CCN2 Next: FDX1

FDFT1 Infographic by Boster Bio

All FDFT1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-FDFT1 Monoclonal Antibody

4 Q&As

All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M05118
100 μl

Anti-Squalene synthase FDFT1 Antibody

Western blot analysis of extracts of various cell lines, using SQS/FDFT1 antibody at 1:500 dilution

Immunofluorescence analysis of NIH-3T3 cells using SQS/FDFT1 antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded mouse testis using SQS/FDFT1 antibody at dilution of 1:100

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A05118
100ul

Human FDFT1 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$250
Cat # PROTP37268
Starting from 10ug

Anti-FDFT1 Mouse Monoclonal Antibody [Clone ID: OTI1H9]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FDFT1 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-FDFT1 monoclonal antibody at 1:200 dilution

Western blot analysis of extracts (10ug) from a mouse tissues by using anti-FDFT1 monoclonal antibody (1:200)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M05118-1
100 µl

Anti-FDFT1 Mouse Monoclonal Antibody [Clone ID: OTI2F10]

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-FDFT1 monoclonal antibody

Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-FDFT1 mouse monoclonal antibody

+10

Human, Monkey, Mouse, Rat

IF, IHC, WB

$523
Cat # M05118-2
100 µl

FDFT1 (NM_004462) Human Over-expression Lysate

Human

$628
Cat # LS002222
20 µg, 100 µg

Anti-FDFT1 Antibody

Human, Mouse

ELISA, IF, IHC, ICC, WB

$370
Cat # A05118-1
100 μl/vial

FDFT1 Overview

Facts about Squalene synthase.

FDFT1 3D structure. Source: alphafold

Squalene synthase (FDFT1)

Gene Information

Human
Gene Name:	FDFT1
Uniprot:	P37268
Entrez:	2222

Family

Belongs to:

phytoene/squalene synthase family

Alternative Names

DGPT; EC 2.5.1.21; ERG9; farnesyl-diphosphate farnesyltransferase 1; Farnesyl-diphosphate farnesyltransferase; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SQS; squalene synthase; squalene synthetase; SS

Molecular Weight

Mass (kDA):
48.115 kDA

Genomic Context


Human

Location:	8p23.1
Sequence:	8; NC_000008.11 (11795573..11839309)

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Cardiovascular Diseases
Tissue Adhesions
Obesity
Stomach Neoplasms
Neoplasms
Hyperlipidemia
Esophageal Neoplasms
Adenocarcinoma
Diabetes Mellitus
Inflammation
Alzheimer's Disease
Fracture Of First Cervical Vertebra

Brain Ischemia
Melanoma
Hypoxia
Infertility
Fibrosis
Esophageal Adenocarcinoma
Fatty Liver

Pathways

Transport
Cell Adhesion
Cell Proliferation
Dna Repair
Neurogenesis
Localization
Cholesterol Transport
Cholesterol Homeostasis
Secretion
Response To Hypoxia
Aging
Ion Transport
Oxidative Phosphorylation

Glucose Homeostasis
Methylation
Cell Death
Cell Cycle
Pathogenesis
Fatty Acid Oxidation
Cellular Response To Hypoxia

PTMs

Phosphorylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FDFT1

References

PMID: 8474436 by Robinson G.W., et al. Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation.

PMID: 7685352 by Jiang G., et al. Transcriptional regulation by lovastatin and 25-hydroxycholesterol in HepG2 cells and molecular cloning and expression of the cDNA for the human hepatic squalene synthase.