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- Table of Contents
FHL1 Antibodies
AND FHL1 ELISA kits, FHL1 Proteins
Many biological assays use antibodies to detect FHL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FHL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FHL1 antibodies...
Designing a Western blot for FHL1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the FHL1 Western Blot GuideFHL1 Infographic by Boster Bio
All FHL1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01258-1
100 μg/vial
Cat # A01258-1
100 μg/vial
FHL1 Overview
Facts about Four and a half LIM domains protein 1.
Four and a half LIM domains protein 1 (FHL1)
May have an involvement in muscle growth or hypertrophy. .
Gene Information
| Human | |
|---|---|
| Gene Name: | FHL1 |
| Uniprot: | Q13642 |
| Entrez: | 2273 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
bA535K18.1; FHL1; four and a half LIM domains 1; HLH1; HPLH1; KYOT; KYO-T; LIM protein SLIMMER; skeletal muscle LIM-protein1; SLIM1; SLIM1Isl-1 and Mec-3 domains 1; SLIMMER; XMPMA
Molecular Weight
Mass (kDA):
36.263 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq26.3 |
| Sequence: | X; NC_000023.11 (136146702..136211359) |
Tissue Specificity
Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood leukocytes. Isoform 2 is expressed in brain, skeletal muscle and to a lesser extent in heart, colon, prostate and small intestine. Isoform 3 is expressed in testis, heart and skeletal muscle.
Subcellular Localizations
[Isoform 1]: Cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus.; [Isoform 2]: Nucleus. Cytoplasm, cytosol. Predominantly nuclear in myoblasts but is cytosolic in differentiated myotubes.
Diseases
- Myopathy
- Hypertrophy
- Cardiomyopathies
- Neoplasms
- Malignant Neoplasms
- Atrophy
- Muscular Atrophy
- Weakness
- Muscular Dystrophy
- Dystrophy
- Carcinoma
- Genetic Diseases, X-linked
Interacting Proteins
- NRIP1
- PPP2CB
- PRNP
Pathways
- Muscle Atrophy
- Localization
- Cell Cycle
- Cell Growth
- Pathogenesis
- Cell Proliferation
- Methylation
- Notch Signaling Pathway
- Ribosome Biogenesis
- Angiogenesis
- Cell Differentiation
- Dna Methylation
- Cell Migration
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Sumoylation
Research Areas
- Apoptosis
- Cancer
- Lipid and Metabolism
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FHL1
bosterbio.com/bosterbio-gene-info-cards/FHL1
References
PMID: 8753811 by Morgan M.J., et al. Slim defines a novel family of LIM-proteins expressed in skeletal muscle.
PMID: 9714789 by Lee S.M.Y., et al. Chromosomal mapping, tissue distribution and cDNA sequence of four- and-a-half LIM domain protein 1 (FHL1).